Results 21 to 30 of about 31,308 (219)
Two-Component Systems in Francisella Species
Frontiers in Cellular and Infection Microbiology, 2019 Bacteria alter gene expression in response to changes in their environment through various mechanisms that include signal transduction systems.
Monique L. van Hoek +5 more
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Systematic Reconstruction of the Complete Two-Component Sensorial Network in
mSystems, 2020 In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different range of signals and controlling ...
B. Rapun-Araiz +6 more
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Frontiers in Microbiology, 2022 Heme is an essential cofactor for almost all living cells by acting as prosthetic group for various proteins or serving as alternative iron source. However, elevated levels are highly toxic for cells. Several corynebacterial species employ two paralogous,
Aileen Krüger, Julia Frunzke
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Visualizing the Pre-Active Conformation of Response Regulator PhoBNF20D in Its apo State
Chinese Journal of Magnetic Resonance, 2019 PhoB is a response regulator of the PhoR/PhoB two-component system (TCS) in Escherichia Coli, which is involved in environmental phosphate regulation. PhoB activation is known to be mediated by Mg2+ coordination and phosphorylation of the conserved D53 ...
KOU Xin-hui +5 more
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Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways. [PDF]
PLoS ONE, 2011 The GraS/GraR two-component system has been shown to control cationic antimicrobial peptide (CAMP) resistance in the major human pathogen Staphylococcus aureus.
Mélanie Falord +4 more
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Cross-regulation in a three-component cell envelope stress signaling system of Brucella
mBio, 2023 A multi-layered structure known as the cell envelope separates the controlled interior of bacterial cells from a fluctuating physical and chemical environment.
Xingru Chen +3 more
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Sensor histidine kinases kdpD and aauS regulate biofilm and virulence in Pseudomonas aeruginosa PA14
Frontiers in Cellular and Infection Microbiology, 2023 Pseudomonas aeruginosa is a multidrug-resistant opportunistic human pathogen that utilizes two-component systems (TCSs) to sense pathophysiological signals and coordinate virulence. P. aeruginosa contains 64 sensor histidine kinases (HKs) and 72 response
Maria Sultan +4 more
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Sensors, 2009 The plant pathogenic bacterium Pseudomonas syringae PG4180 synthesizes high levels of the phytotoxin coronatine (COR) at the virulence-promoting temperature of 18 °C, but negligible amounts at 28 °C. Temperature-dependent COR gene expression is regulated
Alexander Schenk +4 more
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Frontiers in Microbiology, 2017 Kdp-ATPase is an inducible high affinity potassium uptake system that is widely distributed in bacteria, and is generally regulated by the KdpD/KdpE two-component system (TCS).
Jin He +9 more
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Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis.
PLoS Pathogens, 2020 Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a mechanistic understanding of these important signal transduction systems.
Hualiang Pi +10 more
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