Results 21 to 30 of about 20,982,500 (334)
Needle beam two-photon microscopy for simultaneous multiplane neural and vascular imaging in awake mice [PDF]
PhotoniXComprehensive understanding of brain functions necessitates high-speed imaging of neuronal and vascular dynamics across extensive volumes. Functional neuroimaging investigations with two-photon microscopy are commonly hindered by its limited depth of ...
Quanyu Zhou +11 more
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Insight into pericytes in glioblastoma angiogenesis: In vivo tracking by two‐photon microscopy and proteomic profiling [PDF]
Animal Models and Experimental MedicineBackground Glioblastoma (GBM) is a highly aggressive brain tumor characterized by aberrant angiogenesis and an immunosuppressive microenvironment. Pericytes are aberrantly recruited but their spatiotemporal roles and molecular changes remain unclear ...
Qinghong Wang +5 more
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Two-Photon Laser Scanning Microscopy
, 2008 Since its inception more than 15 years ago, two-photon laser scanning microscopy (2PLSM) has found widespread use in biological and medical research. Two-photon microscopy is based on simultaneous absorption of two photons by fluorophores and subsequent ...
Nimmerjahn, A, Theer, P, Helmchen, F
openaire +3 more sources
More than double the fun with two-photon excitation microscopy
Communications BiologyFor generations researchers have been observing the dynamic processes of life through the lens of a microscope. This has offered tremendous insights into biological phenomena that span multiple orders of time- and length-scales ranging from the pure ...
Peter Luu +2 more
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A new phase for two-photon microscopy [PDF]
Frontiers in Neuroscience, 2009 Two-photon excitation has enabled remarkable advances in our understanding of the nervous system. Its three-dimensional resolution, superior depth penetration, and minimal phototoxicity for out-of-focus portions of the sample have made it the technique of choice for an impressive array of applications.
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Two-photon laser scanning fluorescence microscopy using photonic crystal fibre [PDF]
, 2004 We report the application of a simple yet powerful modular pulse compression system, based on photonic crystal fibres which improves upon incumbent twophoton laser scanning fluorescence microscopy techniques.
McConnell, G., Riis, E.
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Scientific Reports, 2021 Magnetic resonance imaging (MRI) of the brain combined with voxel-based morphometry (VBM) revealed changes in gray matter volume (GMV) in various disorders. However, the cellular basis of GMV changes has remained largely unclear. We correlated changes in
Livia Asan +7 more
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Two-Photon Imaging to Unravel the Pathomechanisms Associated with Epileptic Seizures: A Review
Applied Sciences, 2021 Despite extensive research, the exact pathomechanisms associated with epileptic seizure formation and propagation have not been elucidated completely. Two-photon imaging (2PI) is a fluorescence-based microscopy technique that, over the years, has been ...
Luqman Khan +7 more
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Planar Airy beam light-sheet for two-photon microscopy [PDF]
Biomedical Optics Express, 2020 We demonstrate the first planar Airy light-sheet microscope. Fluorescence light-sheet microscopy has become the method of choice to study large biological samples with cellular or sub-cellular resolution. The propagation-invariant Airy beam enables a ten-
N. Hosny +12 more
semanticscholar +1 more source
Comparing confocal and two-photon Ca2+ imaging of thin low-scattering preparations
Biophysical Reports, 2023 Ca2+ imaging provides insight into biological processes ranging from subcellular dynamics to neural network activity. Two-photon microscopy has assumed a dominant role in Ca2+ imaging.
Jinbo Cheng +3 more
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