Results 41 to 50 of about 20,982,500 (334)

MEMS Enabled Miniature Two-Photon Microscopy for Biomedical Imaging

open access: yesMicromachines, 2023
Over the last decade, two-photon microscopy (TPM) has been the technique of choice for in vivo noninvasive optical brain imaging for neuroscientific study or intra-vital microendoscopic imaging for clinical diagnosis or surgical guidance because of its ...
Xiaomin Yu   +4 more
doaj   +1 more source

In vivo imaging with a water immersion objective affects brain temperature, blood flow and oxygenation

open access: yeseLife, 2019
Previously, we reported the first oxygen partial pressure (Po2) measurements in the brain of awake mice, by performing two-photon phosphorescence lifetime microscopy at micrometer resolution (Lyons et al., 2016).
Morgane Roche   +5 more
doaj   +1 more source

Line-Shaped Illumination: A Promising Configuration for a Flexible Two-Photon Microscopy Setup

open access: yesApplied Sciences, 2022
An innovative two-photon microscope exploiting a line-shaped illumination has been recently devised and then implemented. Such configuration allows to carry out a real-time detection by means of standard CCD cameras and is able to maintain the same ...
Jacopo Parravicini   +2 more
doaj   +1 more source

In vivo two-photon microscopy reveals the contribution of Sox9+ cell to kidney regeneration in a mouse model with extracellular vesicle treatment

open access: yesJournal of Biological Chemistry, 2020
Mesenchymal stem cell (MSC)–derived extracellular vesicles (EVs) have been shown to stimulate regeneration in the treatment of kidney injury. Renal regeneration is also thought to be stimulated by the activation of Sox9+ cells.
Kaiyue Zhang   +13 more
semanticscholar   +1 more source

Comparing the fundamental imaging depth limit of two-photon, three-photon, and non-degenerate two-photon microscopy

open access: yesOptics Letters, 2020
We have systematically characterized the degradation of imaging quality with depth in deep brain multi-photon microscopy, utilizing our recently developed numerical model that computes wave propagation in scattering media. The signal-to-background ratio (
Xiaojun Cheng   +5 more
semanticscholar   +1 more source

A simple Bessel module with tunable focal depth and constant resolution for commercial two-photon microscope

open access: yesJournal of Innovative Optical Health Sciences, 2023
The volumetric imaging of two-photon microscopy expands the focal depth and improves the throughput, which has unparalleled superiority for three-dimension samples, especially in neuroscience.
Ting Mo   +6 more
doaj   +1 more source

Two-photon microscopy in pulmonary research [PDF]

open access: yesSeminars in Immunopathology, 2010
As the lung is constantly exposed to both innocuous and potentially noxious antigens, a thorough understanding of both innate and adaptive immune responses in this organ is of the essence. Imaging modalities such as magnetic resonance imaging, positron emission tomography, and confocal microscopy have expanded our knowledge about various molecular ...
Ruben G, Nava   +5 more
openaire   +2 more sources

Encoded multisite two-photon microscopy [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
The advent of scanning two-photon microscopy (2PM) has created a fertile new avenue for noninvasive investigation of brain activity in depth. One principal weakness of this method, however, lies with the limit of scanning speed, which makes optical interrogation of action potential-like activity in a neuronal network problematic.
Mathieu, Ducros   +4 more
openaire   +2 more sources

2-Photon Laser Scanning Microscopy on Native Human Cartilage [PDF]

open access: yes, 2005
Martini J, Tönsing K, Dickob M, Anselmetti D. 2-Photon Laser Scanning Microscopy on Native Human Cartilage. In: Proceedings of SPIE - The International Society for Optical Engineering. Vol 5860.
Michael Dickob   +7 more
core   +1 more source

Controlled Assembly of AIE Active Bolaamphiphilic Macromolecules into Luminescent Organic Nanoparticles Optimized for Two-Photon Microscopy in vivo [PDF]

open access: yes, 2022
The (Z) and (E) isomers of an extended tetraphenylethylene-based chromophore with optimized two-photon induced luminescence properties are separated and functionalized with water-solubilizing pendant polymer groups, promoting their self-assembly in ...
Akos, Banyasz   +13 more
core   +2 more sources

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