Results 21 to 30 of about 2,618 (150)

Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans [PDF]

Cardiovascular Therapeutics
Conclusion: TYMP emerges as a novel regulatory force in vascular biology, influencing VSMC function and inflammatory responses to promote AAA development.
Liang Hong, Hong Yue, Dunpeng Cai, Autumn DeHart, Gretel Toloza-Alvarez, Lili Du, Xianwu Zhou, Xiaoping Fan, Huanlei Huang, Shiyou Chen, Shaik O. Rahaman, Jian Zhuang, Wei Li   +12 more
doaj   +2 more sources

Investigating potential novel therapeutic targets and biomarkers for ankylosing spondylitis using plasma protein screening [PDF]

Frontiers in Immunology
BackgroundAnkylosing spondylitis (AS) is a chronic inflammatory disease affecting the spine and sacroiliac joints. Recent genetic studies suggest certain plasma proteins may play a causal role in AS development.
Wenkang You, Yanbin Lin, Mingzhong Liu, Zhangdian Lin, Rongjie Ye, Canhong Zhang, Rongdong Zeng   +6 more
doaj   +2 more sources

Causal association between plasma proteins and lung adenocarcinoma: a two-sample mendelian randomization study [PDF]

BMC Pulmonary Medicine
Background This study utilized Mendelian randomization (MR) to investigate the causal relationship between circulating plasma proteins and lung adenocarcinoma.
Weiyuan Zhang, Nan Chen, Changxi Li, Xitian Su, Zhuo Fu, Youshuang Zhong, Huojin Deng   +6 more
doaj   +2 more sources

A CEBPB/TYMP/GDF15 signaling axis mediates tumor growth and cisplatin resistance in bladder cancer [PDF]

Translational Oncology
Yundong Xuan
exaly   +2 more sources

Letter to the Editor: Gastrointestinal Pseudo-Obstruction Is Not an Uncommon Phenotypic Manifestation of POLG1 Variants-Authors' Reply. [PDF]

Eur J Neurol
European Journal of Neurology, Volume 33, Issue 6, June 2026.
Capece G, Manara R, Salviati L, Viscomi C, Bello L, Pegoraro E.   +5 more
europepmc   +2 more sources

Thymidine Phosphorylase Is Increased in COVID-19 Patients in an Acuity-Dependent Manner

Frontiers in Medicine, 2021
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), is a human respiratory disease. Hitherto, there is no effective treatment has been established.
Wei Li, Hong Yue
doaj   +1 more source

Новая мутация в гене TYMP: клинико-морфологическая характеристика пациента с синдромом MNGIE [PDF]

, 2022
Mitochondrial neurogastrointestinal encephalomyopathy is an extremely rare (1–9:1 000 000, Orphanet, 2021) multisystem genetic disease caused by mutations in the TYMP gene encoding the enzyme thymidine phosphorylase.The article presents the data of a ...
V. A. Tsargush, A. M. Emelin, P. G. Tsygankova, И. С. Лимаев, E. V. Presnyakov, S. A. Kurbatov, S. N. Bardakov, Н. В. Бакулина, R. V. Deev, I. S. Limaev, N. V. Bakulina, V. Nikitins, E. V. Kolmakova, П. Г. Цыганкова, В. А. Царгуш, С. Н. Бардаков, А. М. Емелин, Е. В. Пресняков, И. А. Чекмарева, Е. В. Колмакова, В. Никитинс, С. А. Курбатов, I. A. Chekmareva, Р. В. Деев   +23 more
core   +1 more source

Optical Coherence Tomography as an Emerging Technique for Identifying Pediatric Middle Ear Effusion. [PDF]

Laryngoscope
This prospective study evaluated optical coherence tomography (OCT) as a diagnostic tool for identifying middle ear effusion (MEE) in 164 pediatric patients. OCT was determined to have a sensitivity of 74% and a specificity of 93%, comparable to otoscopy and tympanometry, with moderate agreement (κ = 0.41) between clinical and non‐clinical raters.
Neuberger R, Carter J, Dives A, Ibarrola ASC, Ixba M, Lambert E, Liu YC, Messner AH.   +7 more
europepmc   +2 more sources

Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR)

Journal of Experimental & Clinical Cancer Research, 2021
Background Pemetrexed (MTA) plus cisplatin combination therapy is considered the standard of care for patients with advanced non-small-cell lung cancer (NSCLC).
Yanyun Gao, Philipp Zens, Min Su, Camila Anna Gemperli, Haitang Yang, Haibin Deng, Zhang Yang, Duo Xu, Sean R. R. Hall, Sabina Berezowska, Patrick Dorn, Ren-Wang Peng, Ralph Alexander Schmid, Wenxiang Wang, Thomas Michael Marti   +14 more
doaj   +1 more source

TYMP (thymidine phosphorylase) [PDF]

, 2010
Review on TYMP (thymidine phosphorylase), with data on DNA, on the protein encoded, and where the gene is ...
Bijnsdorp, IV, GJ Peters, IV Bijnsdorp, Peters, GJ   +3 more
core   +1 more source