Results 31 to 40 of about 4,565,322 (357)

The emerging role of lncRNAs in inflammatory bowel disease

Experimental and Molecular Medicine, 2018
Inflammatory bowel disease: The role of noncoding RNA Studying long noncoding RNAs (lncRNAs) may improve diagnosis and treatment of inflammatory bowel disease (IBD).
Reza Yarani, Aashiq H. Mirza, Simranjeet Kaur, Flemming Pociot   +3 more
doaj   +1 more source

β Cell and Autophagy: What Do We Know?

Biomolecules, 2023
Pancreatic β cells are central to glycemic regulation through insulin production. Studies show autophagy as an essential process in β cell function and fate.
Hamid-Reza Mohammadi-Motlagh, Mona Sadeghalvad, Niloofar Yavari, Rosita Primavera, Setareh Soltani, Shashank Chetty, Abantika Ganguly, Shobha Regmi, Tina Fløyel, Simranjeet Kaur, Aashiq H. Mirza, Avnesh S. Thakor, Flemming Pociot, Reza Yarani   +13 more
doaj   +1 more source

Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes.

New England Journal of Medicine, 2019
BACKGROUND Closed-loop systems that automate insulin delivery may improve glycemic outcomes in patients with type 1 diabetes. METHODS In this 6-month randomized, multicenter trial, patients with type 1 diabetes were assigned in a 2:1 ratio to receive ...
Brown Sa, Kovatchev Bp, Raghinaru D, Lum Jw, Buckingham Ba, Kudva Yc, Laffel Lm, Levy Cj, Pinsker Je, Wadwa Rp, Dassau E, Doyle Fj, Anderson Sm, Church Mm, Dadlani V, Ekhlaspour L, Forlenza Gp, Isganaitis E, Lam Dw, Kollman C, Beck Rw, Trial Research Group. iDCL   +21 more
semanticscholar   +1 more source

Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic

BMJ Open Diabetes Research & Care, 2021
Introduction Lockdown measures have a profound effect on many aspects of daily life relevant for diabetes self-management. We assessed whether lockdown measures, in the context of the COVID-19 pandemic, differentially affect perceived stress, body weight,
M. Ruissen, H. Regeer, Cyril P. Landstra, M. Schroijen, I. Jazet, M. Nijhoff, H. Pijl, B. Ballieux, O. Dekkers, S. Huisman, E. D. de Koning   +10 more
semanticscholar   +1 more source

Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?

Frontiers in Immunology, 2021
In human type 1 diabetes and animal models of the disease, a diverse assortment of immune cells infiltrates the pancreatic islets. CD8+ T cells are well represented within infiltrates and HLA multimer staining of pancreas sections provides clear evidence
Teresa Rodriguez-Calvo, Teresa Rodriguez-Calvo, Gustaf Christoffersson, Gustaf Christoffersson, Christine Bender, Matthias G. von Herrath, Roberto Mallone, Roberto Mallone, Sally C. Kent, Eddie A. James   +9 more
doaj   +1 more source

A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes.

New England Journal of Medicine, 2020
BACKGROUND A closed-loop system of insulin delivery (also called an artificial pancreas) may improve glycemic outcomes in children with type 1 diabetes. METHODS In a 16-week, multicenter, randomized, open-label, parallel-group trial, we assigned, in a ...
M. Breton, L. Kanapka, R. Beck, E. Cengiz   +3 more
semanticscholar   +1 more source

Diabetes, Type 1

, 2007
This chapter provides an overview of the role of psychological stress in Type 1 diabetes. Studies relating to stress and Type 1 diabetes onset and control, as well as the evidence relating to stress management training in people with Type 1 diabetes are discussed.
Riazi, Afsane, Bradley, Clare
openaire   +19 more sources

Recent advances in understanding Type 1 Diabetes [version 1; referees: 2 approved]

F1000Research, 2016
Type 1 diabetes is a multifactorial disease in which genetic and environmental factors play a key role. The triggering event is still obscure, and so are many of the immune events that follow.
Gustaf Christoffersson, Teresa Rodriguez-Calvo, Matthias von Herrath   +2 more
doaj   +1 more source

Type 1 Diabetes at a Crossroads! [PDF]

Diabetes Care, 2015
“Be at a crossroads”: to be at a stage in your life when you have to make a very important decision (1). Type 1 diabetes at a crossroads? What does that really mean? It cannot mean that progress has not been made! Indeed, in the field of diabetes, reporting of new information is clearly outpacing our ability to incorporate new findings into clinical ...
William V. Tamborlane, Jay S. Skyler, William T. Cefalu   +2 more
openaire   +3 more sources

Decline in titers of anti-idiotypic antibodies specific to autoantibodies to GAD65 (GAD65Ab) precedes development of GAD65Ab and type 1 diabetes. [PDF]

PLoS ONE, 2013
The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the healthy immune response the original equilibrium is eventually restored through counter-regulatory ...
Helena Elding Larsson, Ida Jönsson, Ake Lernmark, Sten Ivarsson, Jared R Radtke, Christiane S Hampe, Diabetes Prediction in Skåne (DiPiS), Type 1 Diabetes Trial Network   +7 more
doaj   +1 more source