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Background: Interleukin -6 (IL-6) as the key mediator of the acute phase reaction is of interest .elevated protein concentrations of IL-6 in the blood have been shown in patients with type 2 diabetes. This study aimed to investigate the association of IL-
Maha F. Almelan
doaj +1 more source
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM +15 more
core +1 more source
Recommendations for diabetes type 2
La diabetes es una enfermedad crónica y compleja que requiere de atención médica continua, con intervenciones que van más allá del mero control de la glucemia.
María Cristina Faingold
doaj +1 more source
The incidence of type 2 diabetes in children and adolescents in the United States rose at an annual rate of 4.8% between 2002-2003 and 2014-2015. Type 2 diabetes progresses more aggressively to complications than type 1 diabetes.
Goutham Rao MD, Elizabeth T. Jensen PhD
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Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population [PDF]
Background Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of this
A Helgason +28 more
core +6 more sources
Type 2 diabetes mellitus and gout
Gout is the most common inflammatory arthritis in adults and has continued to increase in prevalence over the past decades. Gout is characterized by hyperuricemia with the obligatory crystallization of urates and an associated inflammatory reaction, as ...
O. V. Zhelyabina, M. S. Eliseev
doaj +1 more source
The association between neighbourhood greenspace and type 2 diabetes in a large cross-sectional study [PDF]
Objective: To investigate the relationship between neighbourhood greenspace and type 2 diabetes. Design: Cross-sectional. Setting: 3 diabetes screening studies conducted in Leicestershire, UK in 2004–2011.
Astell-Burt +38 more
core +1 more source
β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]
ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E +7 more
core +2 more sources
Purpose The ‘Biomarkers of heterogeneity in type 1 diabetes’ study cohort was set up to identify genetic, physiological and psychosocial factors explaining the observed heterogeneity in disease progression and the development of complications in people ...
+31 more
doaj +1 more source
Reversal of Type 2 Diabetes Mellitus
NA
Sudhir Bhandari
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