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Current Opinion in Genetics & Development, 2007 Identification and characterization of genetic variants that either cause or predispose to diabetes are a major focus of biomedical research. As of early 2007, the molecular basis of most forms of monogenic diabetes resulting from beta-cell dysfunction is known and, in particular, there has been recent success in delineating the genetic aetiology of ...
Mark I. McCarthy +2 more
openaire +4 more sources
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes [PDF]
, 2019 OBJECTIVE: Abnormally elevated proinsulin secretion has been reported in type 2 and early type 1 diabetes when significant C-peptide is present. We questioned whether individuals with long-standing type 1 diabetes and low or absent C-peptide secretory
Arvan, Peter +22 more
core +1 more source
Individualizing treatment of type 2 diabetes
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2014 DOI: http://dx.doi.org/10.4038/sjdem.v4i1.7256 Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2014; 4: 56 ...
TP Weerarathna
doaj +1 more source
Peroxisome Proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes [PDF]
, 2005 Dysregulation of fatty acid metabolism is important in the pathogenesis of type 2 diabetes. Peroxisome proliferator-activated receptor (PPAR) is a master regulator of fatty acid catabolism, and PPAR activators delay the onset of type 2 diabetes.
Acharya, J. +7 more
core
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]
, 2016 Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM +15 more
core +1 more source
Sleep disorders in type 2 diabetes
Indian Journal of Endocrinology and Metabolism, 2017 Type 2 diabetes mellitus (T2DM) has shown to be associated with higher incidence of sleep disorders, which may be due to disease itself or because of secondary complications or associated comorbidities associated with diabetes. On the other hand, shorter
Deepak Khandelwal +3 more
doaj +1 more source
Supervised Machine Learning based Ensemble Model for Accurate Prediction of Type 2 Diabetes [PDF]
arXiv, 2019 According to the American Diabetes Association(ADA), 30.3 million people in the United States have diabetes, but only 7.2 million may be undiagnosed and unaware of their condition. Type 2 diabetes is usually diagnosed for most patients later on in life whereas the less common Type 1 diabetes is diagnosed early on in life.
arxiv
A Reinforcement Learning System to Encourage Physical Activity in Diabetes Patients [PDF]
, 2016 Regular physical activity is known to be beneficial to people suffering from diabetes type 2. Nevertheless, most such people are sedentary. Smartphones create new possibilities for helping people to adhere to their physical activity goals, through continuous monitoring and communication, coupled with personalized feedback.
arxiv +1 more source
Arrhythmias in type 2 diabetes mellitus
Indian Journal of Endocrinology and Metabolism, 2017 Chronic hyperglycaemia of Type 2 diabetes mellitus causes long term damage to heart resulting in coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), and sudden death from arrhythmias.
Gaurav Agarwal, Satish Kumar Singh
doaj +1 more source
Diabetes Care, 2013 Reversal of type 2 diabetes to normal metabolic control by either bariatric surgery or hypocaloric diet allows for the time sequence of underlying pathophysiologic mechanisms to be observed. In reverse order, the same mechanisms are likely to determine the events leading to the onset of hyperglycemia and permit insight into the etiology of type 2 ...
openaire +4 more sources