Results 71 to 80 of about 5,917,232 (403)

IL-6 and Type 2 Diabetes

open access: yesمجلة كلية الطب, 2010
Background: Interleukin -6 (IL-6) as the key mediator of the acute phase reaction is of interest .elevated protein concentrations of IL-6 in the blood have been shown in patients with type 2 diabetes. This study aimed to investigate the association of IL-
Maha F. Almelan
doaj   +1 more source

Machine Learning Approaches for Type 2 Diabetes Prediction and Care Management [PDF]

open access: yesarXiv, 2021
Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this document we seek to remedy this omission in literature with an encompassing overview of diabetes complication ...
arxiv  

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.

open access: yesNew England Journal of Medicine, 2001
BACKGROUND It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine slows the progression of nephropathy in patients with type 2 diabetes independently of its capacity to lower the systemic ...
E. Lewis   +9 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Incidence of Type 2 Diabetes in Kuwaiti Children and Adolescents: Results From the Childhood-Onset Diabetes Electronic Registry (CODeR)

open access: yesFrontiers in Endocrinology, 2019
Background: Type 2 Diabetes (T2D) in children and adolescents has become an important public health concern due to the increase in childhood obesity worldwide.
Hessa Al-Kandari   +22 more
doaj   +1 more source

Symptom based Hierarchical Classification of Diabetes and Thyroid disorders using Fuzzy Cognitive Maps [PDF]

open access: yesarXiv, 2021
Fuzzy Cognitive Maps (FCMs) are soft computing technique that follows an approach similar to human reasoning and human decision-making process, making them a valuable modeling and simulation methodology. Medical Decision Systems are complex systems consisting of many factors that may be complementary, contradictory, and competitive; these factors ...
arxiv  

Pathophysiology of Type 2 Diabetes Mellitus

open access: yesInternational Journal of Molecular Sciences, 2020
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia   +7 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Type-2 diabetes

open access: yesAnnals of Internal Medicine
Type 2 diabetes (T2D) is a prevalent disease that increases risk for vascular, renal, and neurologic complications. Prevention and treatment of T2D and its complications are paramount. Many advancements in T2D care have emerged over the past 5 years, including increased understanding of the importance of early intensive glycemic control, mental health,
Skoradal, May-Britt   +4 more
openaire   +5 more sources

Golgi-associated retrograde protein (GARP) complex-dependent endosomes to trans Golgi network retrograde trafficking is controlled by Rab4b

open access: yesCellular & Molecular Biology Letters
Background The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fused to the trans-Golgi network ...
Jérôme Gilleron   +4 more
doaj   +1 more source

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