Results 81 to 90 of about 2,716,569 (343)

Early Maladjustment Schemas in Individuals with and without Type 2 Diabetes Mellitus [PDF]

open access: yes, 2019
Objective. This study explored Early Maladjustment Schemas (EMSs) among individuals with and without type 2 diabetes mellitus and examined potential moderating roles for gender, level of education, and occupation. Methods.
Gholamrezaei, Simin   +5 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Kidneys and Diabetes Mellitus Type 2

open access: yesPočki, 2012
No ...
D.D. Ivanov
doaj   +1 more source

Diabetes mellitus type 2 in adults

open access: yesСахарный диабет, 2020
Public organization “Russian Association of Endocrinologists”. Clinical guidelines. 
Ivan I. Dedov   +34 more
doaj   +1 more source

Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. [PDF]

open access: yes, 2013
ObjectiveWe aimed to identify factors that are independently associated with the metabolic clearance rate of insulin (MCRI) and to examine the association of MCRI with incident type 2 diabetes in nondiabetic Hispanics and African Americans.Research ...
Anderson, Andrea M   +10 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

HYPERTENSION AND DIABETES MELLITUS TYPE 2

open access: yesРациональная фармакотерапия в кардиологии, 2018
Aim. To study the effect of long-term combined antihypertensive therapy with lisinopril plus amlodipine on the parameters of central aortic pressure (CAD) and visceral obesity in patients with arterial hypertension (HT) combined with type 2 diabetes ...
M. E. Statsenko, M. V. Derevyanchenko
doaj   +1 more source

Perceptions of a service redesign by adults living with type 2 diabetes [PDF]

open access: yes, 2009
<b>Aim:</b> This article is a report of a study conducted to explore the perceptions of adults with type 2 diabetes towards the service redesign.
Brown, M.   +4 more
core   +1 more source

TYPE 2 DIABETICS

open access: yesThe Professional Medical Journal, 2007
Objective: To find the relationship between the serum cholesterol andtriglyceroid in type 2 diabetics with different parameters of obesity. Design: Descriptive study. Setting: Al-ShifaMetabolic Center Faisalabad. Period: From January 2003 to June 2005.
MOHAMMAD MOHSIN RANA   +3 more
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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