Results 11 to 20 of about 2,069,243 (304)
Type 2 diabetes foot inflammation prevention reminder socks
HeliyonIt is not easy to determine the time between diagnosis and inflammation in patients with type 2 diabetes foot disease. In severe cases, it can lead to ulceration or even amputation.
Xiangfang Ren
doaj +3 more sources
Induction of sterile type 2 inflammation [PDF]
Nature Materials, 2019 Microparticle debris from prosthetic implants has been shown to induce a type 2 inflammatory response through a Bruton’s tyrosine kinase-dependent signalling pathway.
Dimitri A, de Kouchkovsky +2 more
openaire +2 more sources
Islet inflammation in type 2 diabetes [PDF]
Seminars in Immunopathology, 2019 Metabolic diseases including type 2 diabetes are associated with meta-inflammation. β-Cell failure is a major component of the pathogenesis of type 2 diabetes. It is now well established that increased numbers of innate immune cells, cytokines, and chemokines have detrimental effects on islets in these chronic conditions.
Böni-Schnetzler, Marianne +1 more
openaire +2 more sources
Type 2 inflammation in cystic fibrosis: New insights [PDF]
Pediatric Allergy and Immunology, 2022 AbstractRecently, type 2 inflammation has been recognized as one of the most critical factors participating in the pathogenesis of cystic fibrosis (CF). On the one hand, type 2 inflammation restores tissue homeostasis and contributes to the resolution of inflammation following an injury.
Sara Manti +5 more
openaire +5 more sources
CCL4 Functions as a Biomarker of Type 2 Airway Inflammation
Biomedicines, 2022 Eosinophilic airway inflammatory disease is associated with bronchial asthma, with eosinophilic chronic rhinosinusitis (ECRS) typical of refractory type 2 airway inflammation.
Yoshiki Kobayashi +9 more
doaj +1 more source
Journal of Lipid Research, 2019 Eicosanoids are lipid-mediator molecules with key roles in inflammatory skin diseases, such as psoriasis. Eicosanoids are released close to the source of inflammation, where they elicit local pleiotropic effects and dysregulations.
Cornelia Pipper +8 more
doaj +1 more source
Roles of IL-25 in Type 2 Inflammation and Autoimmune Pathogenesis
Frontiers in Immunology, 2021 Interleukin-17E (IL-25) is a member of the IL-17 cytokine family that includes IL-17A to IL-17F. IL-17 family cytokines play a key role in host defense responses and inflammatory diseases.
Chong Deng +9 more
doaj +1 more source
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]
, 2016 Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans +10 more
core +1 more source
Strategies Targeting Type 2 Inflammation: From Monoclonal Antibodies to JAK-Inhibitors
Biomedicines, 2021 Bronchial asthma and its frequent comorbidity chronic rhinosinusitis (CRS), are characterized by an inflammatory process at lower and upper respiratory tract, with a variability in terms of clinical presentations (phenotypes) and distinct underpin ...
Andrea Matucci +4 more
doaj +1 more source
IL-1α and TNF-α Down-Regulate CRH Receptor-2 mRNA Expression in the Mouse Heart [PDF]
, 2001 Two receptors (CRH receptor type 1 and CRH receptor type 2) have been identified for the stress-induced neuropeptide, CRH and related peptides, urocortin, and urocortin II.
Coste, Sarah C. +4 more
core +2 more sources