Results 21 to 30 of about 1,471,209 (258)
Strategies Targeting Type 2 Inflammation: From Monoclonal Antibodies to JAK-Inhibitors
Biomedicines, 2021 Bronchial asthma and its frequent comorbidity chronic rhinosinusitis (CRS), are characterized by an inflammatory process at lower and upper respiratory tract, with a variability in terms of clinical presentations (phenotypes) and distinct underpin ...
Andrea Matucci +4 more
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Role of type 2 immunity in intestinal inflammation [PDF]
Current Opinion in Gastroenterology, 2015 Type 2 (Th2) immune responses play important roles in intestinal immunity by contributing to the maintenance of mucosal homeostasis, not only conferring protection against helminthic infection but also participating in pro-inflammatory pathways in chronic intestinal inflammatory disorders, including inflammatory bowel disease.
Bamias, G., Cominelli, F.
openaire +3 more sources
Biological targeted therapy for type 2 inflammation bronchial asthma [PDF]
Xin yixueBronchial asthma is a chronic inflammatory disease of the airway involving multiple inflammatory cells and cytokines. Severe asthma is characterized by recurrent attacks and persistent symptoms such as coughing， chest tightness， shortness of breath， and ...
ZHANG Mingqiang, MU Xiangdong
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Sex Differences in IL-33-Induced STAT6-Dependent Type 2 Airway Inflammation
Frontiers in Immunology, 2019 Sex differences in asthma prevalence are well-documented but poorly understood. Murine models have contributed to our understanding of mechanisms that could regulate this sex disparity, though the majority of these studies have examined responses present
Hedi Zhao +6 more
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RAGE-mediated inflammation, type 2 diabetes and diabetic vascular complication
Frontiers in Endocrinology, 2013 Obesity is associated with inflammation and type 2 diabetes. Innate immune system comprised of cellular and molecular components plays an important role in the inflammatory reactions.
Yasuhiko eYamamoto, Hiroshi eYamamoto
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Type 2 diabetes foot inflammation prevention reminder socks
HeliyonIt is not easy to determine the time between diagnosis and inflammation in patients with type 2 diabetes foot disease. In severe cases, it can lead to ulceration or even amputation.
Xiangfang Ren
doaj +1 more source
Type 2 Inflammation and Its Role in Dermatologic Diseases. [PDF]
Int J DermatolABSTRACT Atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria are immune‐mediated, inflammatory skin conditions characterized by intense itch and disease‐specific skin lesions. Despite their different clinical presentations, the three diseases are unified by an aberrant type 2 immune response involving type 2 ...
Chovatiya R +5 more
europepmc +3 more sources
Inflammation and the Incidence of Type 2 Diabetes [PDF]
Diabetes Care, 2010 OBJECTIVE Many studies have documented associations between inflammation and type 2 diabetes incidence. We assessed potential variability in this association in the major U.S. racial/ethnic groups. RESEARCH DESIGN AND METHODS Incident ...
Alain G. Bertoni +8 more
openaire +1 more source
Dupilumab improve acquired reactive perforating collagenosis characterized by type 2 inflammation
Frontiers in Immunology, 2023 BackgroundAcquired reactive perforating collagenosis (ARPC) is a clinically challenging disease with an unclear pathogenesis.ObjectiveTo evaluate the efficacy and safety of dupilumab for the treatment of ARPC, and analyze the expression of type 2 ...
Ben Liu +5 more
doaj +1 more source