Results 11 to 20 of about 102,290,503 (289)

Biological targeted therapy for type 2 inflammation bronchial asthma [PDF]

open access: yesXin yixue
Bronchial asthma is a chronic inflammatory disease of the airway involving multiple inflammatory cells and cytokines. Severe asthma is characterized by recurrent attacks and persistent symptoms such as coughing, chest tightness, shortness of breath, and ...
ZHANG Mingqiang, MU Xiangdong
doaj   +3 more sources

Type 2 airway inflammation in COPD [PDF]

open access: yesEuropean Respiratory Journal
Globally, nearly 400 million persons have COPD, and COPD is one of the leading causes of hospitalisation and mortality across the world. While it has been long-recognised that COPD is an inflammatory lung disease, dissimilar to asthma, type 2 inflammation was thought to play a minor role.
Francesca, Polverino, Don D, Sin
openaire   +3 more sources

Examining the Role of Type 2 Inflammation in Eosinophilic Esophagitis

open access: yesGastro Hep Advances, 2022
Eosinophilic esophagitis (EoE) is a chronic type 2 inflammatory disease characterized by an eosinophilic inflammatory infiltrate in the esophagus, leading to remodeling, stricture formation, and fibrosis.
Mirna Chehade   +11 more
doaj   +3 more sources

Contributions of innate type 2 inflammation to adipose function [PDF]

open access: yesJournal of Lipid Research, 2019
A critical contributor to the health consequences of the obesity epidemic is dysregulated adipose tissue (AT) homeostasis. While white, brown, and beige AT function is altered in obesity-related disease, white AT is marked by progressive inflammation and
W. Reid Bolus, Alyssa H. Hasty
doaj   +3 more sources

Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis [PDF]

open access: yesJID Innovations, 2022
Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple interacting systems. In AD, skin inflammation is caused by host–environment interactions involving keratinocytes as well as tissue-resident immune cells such as ...
Lisa A. Beck   +6 more
doaj   +2 more sources

Exploring the Interplay between Fatty Acids, Inflammation, and Type 2 Diabetes

open access: yesImmuno
Around 285 million people worldwide currently have type 2 diabetes and it is projected that this number will be surpassed by 2030. Therefore, it is of the utmost importance to enhance our comprehension of the disease’s development. The regulation of diet,
Dequina A. Nicholas   +6 more
doaj   +2 more sources

Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations

open access: yesCentral European Journal of Immunology
Introduction In adult-onset asthma, two major endotypes have been proposed: T2 with eosinophilia and non-T2 characterised by neutrophils and interleukin (IL)-17. The objective of the study was to examine the endotype marker profile in patients with severe asthma who were hospitalized for exacerbations, with a ...
Kosar M. Ali   +6 more
doaj   +4 more sources

High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]

open access: yes, 2010
Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli   +7 more
core   +6 more sources

Islet inflammation in type 2 diabetes [PDF]

open access: yesSeminars in Immunopathology, 2019
Metabolic diseases including type 2 diabetes are associated with meta-inflammation. β-Cell failure is a major component of the pathogenesis of type 2 diabetes. It is now well established that increased numbers of innate immune cells, cytokines, and chemokines have detrimental effects on islets in these chronic conditions.
Böni-Schnetzler M, Meier DT
openaire   +3 more sources

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