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Exploring the Interplay between Fatty Acids, Inflammation, and Type 2 Diabetes
ImmunoAround 285 million people worldwide currently have type 2 diabetes and it is projected that this number will be surpassed by 2030. Therefore, it is of the utmost importance to enhance our comprehension of the disease’s development. The regulation of diet,
Dequina A. Nicholas +6 more
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Type 2 inflammation, bronchiectasis and clinical trials: expanding from MAHALE [PDF]
ERJ Open ResearchB. Shoshana Zha +1 more
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High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]
, 2010 Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli +7 more
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Correlation between bullous pemphigoid and type 2 inflammation
Pifu-xingbing zhenliaoxue zazhi, 2022 Bullous pemphigoid (BP) is one of the common autoimmune blister diseases that mainly affects the elderly. Most bullous pemphigoid patients have obvious symptom of pruritus, accompanied by elevated levels of serum total IgE, peripheral blood eosinophils ...
Yao ZHOU +6 more
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Islet inflammation in type 2 diabetes [PDF]
Seminars in Immunopathology, 2019 Metabolic diseases including type 2 diabetes are associated with meta-inflammation. β-Cell failure is a major component of the pathogenesis of type 2 diabetes. It is now well established that increased numbers of innate immune cells, cytokines, and chemokines have detrimental effects on islets in these chronic conditions.
Böni-Schnetzler M, Meier DT
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Induction of sterile type 2 inflammation [PDF]
Nature Materials, 2019 Microparticle debris from prosthetic implants has been shown to induce a type 2 inflammatory response through a Bruton’s tyrosine kinase-dependent signalling pathway.
Dimitri A, de Kouchkovsky +2 more
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Inflammation and the etiology of type 2 diabetes [PDF]
Diabetes/Metabolism Research and Reviews, 2005 AbstractType 2 diabetes is increasingly common worldwide and is beginning to strike younger age groups. Almost 90% of all patients with diabetes show insulin resistance, which also precedes the first symptoms of diabetes. The mechanisms underlying the development of insulin resistance are not well understood.
Ake, Sjöholm, Thomas, Nyström
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Nitric oxide in acute and chronic inflammation. [PDF]
, 2002 PhDNitric oxide (NO) is a signalling molecule formed when L-arginine is converted to L-citrulline by the enzyme NO synthase (NOS. NOS exists as three isoforms, ecNOS is constitutively expressed in endothelial cells and nNOS in neuronal cells, while a ...
Paul-Clark, Mark John
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Type 2 inflammation in asthma and other airway diseases
ERJ Open Research, 2022 Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic COPD and allergic rhinitis are a global health concern.
Jorge Maspero +11 more
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Type 2 inflammatory diseases in atopic dermatitis: A short review
Indian Journal of Paediatric Dermatology, 2022 Type 2 inflammatory diseases are characterized by the dysregulation of the T helper (Th) 2 pathway, the prototype being atopic dermatitis (AD). The common inflammatory pathways, genetic risk factors, epidermal barrier dysfunction, parental atopy, and ...
Ankita Choudhary +3 more
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