Results 191 to 200 of about 533,494 (308)

Macrophages and autophagy: partners in crime

The FEBS Journal, EarlyView.
Autophagy is a key regulator of macrophage function, influencing critical processes like polarization, cytokine secretion, and phagocytosis. Its impact on macrophage behavior varies across different tissues and disease contexts, where it can either promote protective responses or contribute to detrimental outcomes, depending on the physiological or ...
Alessandra Vitaliti, Alessio Reggio, Alessandro Palma   +2 more
wiley   +1 more source

Virulence profile of pathogenic yeasts from snakes: Alternative ways for antifungal strategies. [PDF]

PLoS One
Ugochukwu ICI, Mendoza-Roldan JA, Miglianti M, Palazzo N, Odigie AE, Otranto D, Cafarchia C.   +6 more
europepmc   +1 more source

A phospholipase A₁ antibacterial Type VI secretion effector interacts directly with the C‐terminal domain of the VgrG spike protein for delivery

, 2015
Nicolas Flaugnatti, Thi Thu Le, Stéphane Canaan, Marie‐Stéphanie Aschtgen, Van Son Nguyen, Stéphanie Blangy, Christine Kellenberger, Alain Roussel, Christian Cambillau, Éric Cascales, Laure Journet   +10 more
openalex   +1 more source

Arabidopsis Type-III Phosphatidylinositol 4-Kinases β1 and β2 are Upstream of the Phospholipase C Pathway Triggered by Cold Exposure [PDF]

, 2012
Elise Delage, Éric Ruelland, Isabelle Guillas, Alain Zachowski, Juliette Puyaubert   +4 more
openalex   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Animal Venoms and Their Components: Molecular Mechanisms of Action V 2.0. [PDF]

Toxins (Basel)
Utkin Y.
europepmc   +1 more source

Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin domains 1 and 6-7-8 in patients with idiopathic membranous nephropathy

Xiaobin Liu, Jing Xue, Ting Li, Qingqing Wu, Huiming Sheng, Xue Yang, Bo Lin, Xiumei Zhou, Yuan Qin, Zijian Huang, Le‐Ting Zhou, Liang Wang, Zhigang Hu, Biao Huang   +13 more
openalex   +2 more sources

Neuromedin S Increases L-type Ca²⁺Channel Currents Through G_ia-protein and Phospholipase C-dependent Novel Protein Kinase C Delta Pathway in Adult Rat Ventricular Myocytes [PDF]

, 2012
Run-Xiang Chen, Feng Liu, Yong Li, Guang-An Liu   +3 more
openalex   +1 more source

Fatty‐acid amide hydrolase inhibition mitigates Alzheimer's disease progression in mouse models of amyloidosis

The FEBS Journal, EarlyView.
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Giacomo Giacovazzo, Francesca Ciaramellano, Daniel Tortolani, Alessandro Leuti, Rita Businaro, Federica Armeli, Andras Bilkei‐Gorzo, Roberto Coccurello, Andreas Zimmer, Mauro Maccarrone   +12 more
wiley   +1 more source

Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca: De Novo Assembly and Analysis of Novel Toxic Proteins. [PDF]

Toxins (Basel)
Espín-Angulo J, Vela D.
europepmc   +1 more source