Results 41 to 50 of about 707 (287)

Production of Phospholipase C (Alpha-toxin), Haemolysins and Lethal Toxins by Clostridium perfringens Types A to D [PDF]

Journal of General Microbiology, 1976
To obtain high yields of extracellular enzymes and toxins for immunological analysis, type culture collection strains of Clostridium perfringens types A to D and 28 fresh isolates of C. perfringens type A from humans were grown in fermenters under controlled conditions in a pre-reduced proteose peptone medium.
R, Möllby, T, Holme, C E, Nord, C J, Smyth, T, Wadström   +4 more
openaire   +2 more sources

Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins

Toxins, 2015
Nicotinic acetylcholine receptors (nAChRs) fulfill a variety of functions making identification and analysis of nAChR subtypes a challenging task. Traditional instruments for nAChR research are d-tubocurarine, snake venom protein α-bungarotoxin (α-Bgt ...
Denis Kudryavtsev, Irina Shelukhina, Catherine Vulfius, Tatyana Makarieva, Valentin Stonik, Maxim Zhmak, Igor Ivanov, Igor Kasheverov, Yuri Utkin, Victor Tsetlin   +9 more
doaj   +1 more source

Venom Proteomics of Trimeresurus gracilis, a Taiwan-Endemic Pitviper, and Comparison of Its Venom Proteome and VEGF and CRISP Sequences with Those of the Most Related Species

Toxins, 2023
Trimeresurus gracilis is an endemic alpine pitviper in Taiwan with controversial phylogeny, and its venom proteome remains unknown. In this study, we conducted a proteomic analysis of T.
Tsz-Chun Tse, Inn-Ho Tsai, Yuen-Ying Chan, Tein-Shun Tsai   +3 more
doaj   +1 more source

Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle [PDF]

, 2019
Autotransporters, or type 5 secretion systems, are widespread surface proteins of Gram-negative bacteria often associated with virulence functions. Autotransporters consist of an outer membrane β-barrel domain and an exported passenger.
Slade, DJ, Leo, JC, Leo, Jack Christopher, Trunk, T, Trunk, Thomas, Yoo, CC, Slade, Daniel J., Yoo, Christopher C., Casasanta, MA, Casasanta, Michael   +9 more
core   +1 more source

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

, 2002
International audiencePhospholipases C play a role in the pathogenesis of several bacteria. Mycobacterium tuberculosis, the causative agent of tuberculosis, possesses four genes encoding putative phospholipases C, plcA, plcB, plcC and plcD.
Bordat, Yann, GICQUEL B., Gicquel, Brigitte, BORDAT Y., Raynaud, Catherine, Rauzier, Jean, GUILHOT C., PELICIC V, RAYNAUD C., JACKSON M., SMITH I., Guilhot, Christophe, MANGANELLI, RICCARDO, RAUZIER J., Pelicic, V., Smith, Issar, Jackson, Mary   +16 more
core   +1 more source

Plant Phospholipases: An Overview

, 2012
Plant phospholipases can be grouped into four major types, phospholipase D, phospholipase C, phospholipase A1 (PLA 1), and phospholipase A2 (PLA 2), that hydrolyze glycerophospholipids at different ester bonds.
Stephen Ryu, Xuemin Wang, G Wang, Stephen Beungtae Ryu, X Wang, Geliang Wang   +5 more
core   +1 more source

Vipera berus berus Venom from Russia: Venomics, Bioactivities and Preclinical Assessment of Microgen Antivenom

Toxins, 2019
The common European adder, Vipera berus berus, is a medically relevant species, which is widely distributed in Russia and thus, is responsible for most snakebite accidents in Russia.
Ruslan I. Al-Shekhadat, Ksenia S. Lopushanskaya, Álvaro Segura, José María Gutiérrez, Juan J. Calvete, Davinia Pla   +5 more
doaj   +1 more source

Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction

, 2005
International audiencePhospholipases play an important role as virulence factors in human pathogens. Candida albicans, the major fungal pathogen of humans, encodes phospholipases of type A, B, C and D. Type B Plb2 and type D Pld1 phospholipases have been
Ibrahim-Granet, Oumaïma, d'Enfert, Christophe, Knechtle, Philipp, Brachat, Sophie, Goyard, Sophie   +4 more
core   +1 more source

Oxidative Stress-Induced Destruction of the Yeast C-Type Cyclin Ume3p Requires Phosphatidylinositol-Specific Phospholipase C and the 26S Proteasome [PDF]

Molecular and Cellular Biology, 1999
The yeast UME3 (SRB11/SSN3) gene encodes a C-type cyclin that represses the transcription of the HSP70 family member SSA1. To relieve this repression, Ume3p is rapidly destroyed in cells exposed to elevated temperatures. This report demonstrates that Ume3p levels are also reduced in cultures subjected to ethanol shock, oxidative stress, or carbon ...
Katrina F. Cooper, Michael J. Mallory, Randy Strich   +2 more
openalex   +3 more sources

Snake C-type lectin-like proteins and platelet receptors

, 2006
Snake venoms are complex mixtures of biologically active proteins and peptides. Many affect haemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Snake venom components are classified into various families,
Clemetson, Kenneth John, Lu, Qiumin, Clemetson, Jeannine   +2 more
core   +1 more source