Pancreatic phospholipase A2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk [PDF]
, 2002 Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two ...
Aufenanger, Johannes +5 more
core +1 more source
Toxins, 2019 The common European adder, Vipera berus berus, is a medically relevant species, which is widely distributed in Russia and thus, is responsible for most snakebite accidents in Russia.
Ruslan I. Al-Shekhadat +5 more
doaj +1 more source
Characterization of a Novel Member of the Macrophage Mannose Receptor Type C Lectin Family*
Journal of Biological Chemistry, 1996 The recognition of a diversity of carbohydrates by the various calcium dependent (type C) lectin family members has been shown to be critical for a variety of processes ranging from cell adhesion to antigen presentation.
Kai Wu, Jean Q. Yuan, L. Lasky
semanticscholar +1 more source
Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]
, 2010 The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core +1 more source
Oxidative Stress-Induced Destruction of the Yeast C-Type Cyclin Ume3p Requires Phosphatidylinositol-Specific Phospholipase C and the 26S Proteasome [PDF]
Molecular and Cellular Biology, 1999 The yeast UME3 (SRB11/SSN3) gene encodes a C-type cyclin that represses the transcription of the HSP70 family member SSA1. To relieve this repression, Ume3p is rapidly destroyed in cells exposed to elevated temperatures. This report demonstrates that Ume3p levels are also reduced in cultures subjected to ethanol shock, oxidative stress, or carbon ...
Katrina F. Cooper +2 more
openaire +3 more sources
American Journal of Physiology-Endocrinology and Metabolism, 2008 The parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor (PTH1R) belongs to family B of seven-transmembrane-spanning receptors and is activated by PTH and PTHrP. Upon PTH stimulation, the rat PTH1R becomes phosphorylated at seven serine residues.
Susanne U. Miedlich +1 more
openalex +5 more sources
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
, 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo +4 more
core +2 more sources
Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico
Toxins, 2018 Rattlesnake venoms may be classified according to the presence/absence and relative abundance of the neurotoxic phospholipases A 2 s (PLA 2 s), such as Mojave toxin, and snake venom metalloproteinases (SVMPs).
Miguel Borja +10 more
doaj +1 more source
Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo. [PDF]
, 2013 In this study, we characterized early biochemical changes associated with sertraline and placebo administration and changes associated with a reduction in depressive symptoms in patients with major depressive disorder (MDD).
Bogdanov, MB +11 more
core +2 more sources
Platelets, 1992 Human platelet cytosol contains several phosphoinositide-specific phospholipases C (PLCs) separable by stepwize ion-exchange chromatographies [Banno, Yu, Nakashima, Homma, Takenawa and Nozawa Biochem Biophys Res Commun 1990 167; 396-401]. In the present study, one type of PLC (cPIP(2)-PLC) for which phosphatidylinositol 4,5-bisphosphate (PIP(2)) was ...
T. Suzuki +2 more
openaire +3 more sources