Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils [PDF]
, 2017 Secreted phospholipases A2 (sPLA2s) are extracellular enzymes that catalyze the release of free fatty acids and lysophospholipids from membrane phospholipids and also bind to different receptors (e.g., PLA2R1 or integrins).
Borriello, Francesco +11 more
core +2 more sources
Effective antiprotease-antibiotic treatment of experimental anthrax [PDF]
, 2005 BACKGROUND: Inhalation anthrax is characterized by a systemic spread of the challenge agent, Bacillus anthracis. It causes severe damage, including multiple hemorrhagic lesions, to host tissues and organs.
Alibek, Ken +8 more
core +3 more sources
Induction of Secreted Type IIA Phospholipase A2 Gene Transcription by Interleukin-1β [PDF]
Journal of Biological Chemistry, 2000 Secreted type IIA phospholipase A(2), which is involved in arachidonic acid release, is abundantly produced by chondrocytes and secreted in the synovial fluids of patients affected by rheumatoid arthritis. Transfection experiments showed that interleukin-1beta stimulates the phospholipase A(2) [-1614; +20] promoter activity by 6-7-fold and that the ...
Jean-Luc Olivier +6 more
openaire +3 more sources
The action of human and rabbit serum phospholipase A2 on Escherichia coli phospholipids.
Journal of Lipid Research, 1980 We have compared the properties of phospholipase A (E.C. 3.1.1.4) activity in whole human and rabbit serum toward the phospholipids of Escherichia coli. Using as substrate E.
L Kaplan-Harris +4 more
doaj
Combining phospholipases and a liquid lipase for one-step biodiesel production using crude oils [PDF]
, 2014 Background Enzymatic biodiesel is becoming an increasingly popular topic in bioenergy literature because of its potential to overcome the problems posed by chemical processes.
Cesarini, Silvia +3 more
core +2 more sources
PLoS ONE, 2014 Phospholipases A2 represent the most abundant family of snake venom proteins. They manifest an array of biological activities, which is constantly expanding. We have recently shown that a protein bitanarin, isolated from the venom of the puff adder Bitis
C. Vulfius +9 more
semanticscholar +1 more source
Extracellular Paracoccidioides brasiliensis phospholipase B involvement in alveolar macrophage interaction [PDF]
, 2010 Background: Phospholipase B (PLB) has been reported to be one of the virulence factors for human pathogenic fungi and has also been described as necessary for the early events in infection.
Andrade, Rosângela Vieira de +5 more
core +4 more sources
Demonstration of Functionally Different Interactions between Phospholipase C-γ and the Two Types of Platelet-derived Growth Factor Receptors [PDF]
Journal of Biological Chemistry, 1995 Phosphorylated tyrosine residues in receptor tyrosine kinases serve as binding sites for signal transduction molecules. We have identified two autophosphorylation sites, Tyr-988 and Tyr-1018, in the platelet-derived growth factor (PDGF) alpha-receptor carboxyl-terminal tail, which are involved in binding of phospholipase C-gamma (PLC-gamma).
Anders Eriksson +8 more
openaire +3 more sources
PLoS Pathogens, 2009 The hemolytic phospholipase C (PlcHR) expressed by Pseudomonas aeruginosa is the original member of a Phosphoesterase Superfamily, which includes phosphorylcholine-specific phospholipases C (PC-PLC) produced by frank and opportunistic pathogens.
Michael L Vasil +6 more
doaj +1 more source
Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom [PDF]
, 2010 The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is
BARBOSA, AM +6 more
core +2 more sources