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Suppression of type III effector secretion by polymers [PDF]

open access: yesOpen Biology, 2013
Bacteria secrete effector proteins required for successful infection and expression of toxicity into host cells. The type III secretion apparatus is involved in these processes.
Takashi Ohgita   +3 more
doaj   +4 more sources

Type III secretion in Yersinia: injectisome or not? [PDF]

open access: yesPLoS Pathogens, 2012
Under certain conditions, pathogens like Yersinia secrete high levels of proteins. This ability correlates with cytotoxicity and virulence. The complete inactivity of the secreted proteins when added directly to host cells stimulated research to disclose this “non-AB toxin mechanism” of virulence, and eventually led to the discovery of the type III ...
Tomas Edgren   +3 more
doaj   +5 more sources

Type III secretion system [PDF]

open access: yesCurrent Biology, 2014
The type III secretion system (T3SS) is a membrane-embedded nanomachine found in several Gram-negative bacteria. Upon contact between bacteria and host cells, the syringe-like T3SS (Figure 1) transfers proteins termed effectors from the bacterial cytosol to the cytoplasm or the plasma membrane of a single target cell.
Puhar, Andrea, Sansonetti, Philippe J.
openaire   +2 more sources

Fueling type III secretion [PDF]

open access: yesTrends in Microbiology, 2015
Type III secretion systems (T3SSs) are complex nanomachines that export proteins from the bacterial cytoplasm across the cell envelope in a single step. They are at the core of the machinery used to assemble the bacterial flagellum, and the needle complex many Gram-negative pathogens use to inject effector proteins into host cells and cause disease ...
Pei-Chung, Lee, Arne, Rietsch
openaire   +2 more sources

Type III Secretion Systems and Disease [PDF]

open access: yesClinical Microbiology Reviews, 2007
SUMMARY Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-negative pathogens with a unique virulence mechanism enabling them to inject bacterial effector proteins directly into the host cell cytoplasm, bypassing the extracellular milieu.
Bryan, Coburn   +2 more
openaire   +2 more sources

Translation/Secretion Coupling by Type III Secretion Systems [PDF]

open access: yesCell, 2000
Type III secretion systems mediate export of virulence proteins and flagellar assembly subunits in Gram-negative bacteria. Chaperones specific to each class of secreted protein are believed to prevent degradation of the secreted substrates. We show that an additional role of chaperones may be to regulate translation of secreted proteins.
Karlinsey, Joyce E   +3 more
openaire   +2 more sources

Type III secretion: The bacteria-eukaryotic cell express [PDF]

open access: yesFEMS Microbiology Letters, 2005
Type III secretion (T3S) is an export pathway used by Gram-negative pathogenic bacteria to inject bacterial proteins into the cytosol of eukaryotic host cells. This pathway is characterized by (i) a secretion nanomachine related to the bacterial flagellum, but usually topped by a stiff needle-like structure; (ii) the assembly in the eukaryotic cell ...
Mota, L. J., Sorg, I., Cornelis, G. R.
openaire   +3 more sources

Type III chaperones & Co in bacterial plant pathogens: a set of specialized bodyguards mediating effector delivery

open access: yesFrontiers in Plant Science, 2013
Gram-negative plant pathogenic bacteria possess a type III secretion system (T3SS) to inject bacterial proteins, called type III effectors (T3Es), into host cells through a specialized syringe structure. T3Es are virulence factors that can suppress plant
David eLohou   +8 more
doaj   +1 more source

ATPase-independent type-III protein secretion in Salmonella enterica. [PDF]

open access: yesPLoS Genetics, 2014
Type-III protein secretion systems are utilized by gram-negative pathogens to secrete building blocks of the bacterial flagellum, virulence effectors from the cytoplasm into host cells, and structural subunits of the needle complex.
Marc Erhardt   +3 more
doaj   +1 more source

Biological Activity of Harpin Produced by Pantoea stewartii subsp. stewartii

open access: yesMolecular Plant-Microbe Interactions, 2001
Pantoea stewartii subsp. stewartii causes Stewart's wilt of sweet corn. A hypersensitive response and pathogenicity (Hrp) secretion system is needed to produce water-soaking and wilting symptoms in corn and to cause a hypersensitive response (HR) in ...
Musharaf Ahmad   +5 more
doaj   +1 more source

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