Genome Analysis Identifies a Novel Type III Secretion System (T3SS) Category in Vibrio Species. [PDF]
The nanomachine referred to as the type III secretion system (T3SS) is used by many Gram-negative pathogens or symbionts to inject their effector proteins into host cells to promote their infections or symbioses. Among the genera possessing T3SS is Vibrio, which consists of diverse species of Gammaproteobacteria including human pathogenic species and ...
Zakaria D +4 more
europepmc +5 more sources
Beyond pathogenicity: applications of the type III secretion system (T3SS) of <i>Pseudomonas aeruginosa</i>. [PDF]
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa employs its type III secretion system (T3SS) as a pivotal factor in facilitating the injection of effector proteins into host cells. This process disrupts cellular machinery and immune responses, thereby increasing the pathogen’s survival rates.
Su T +5 more
europepmc +5 more sources
Computational approach to predict species-specific type III secretion system (T3SS) effectors using single and multiple genomes. [PDF]
of Computational approach to predict species-specific type III secretion system (T3SS) effectors using single and multiple ...
Hobbs CK +5 more
europepmc +7 more sources
The Type III Secretion System (T3SS)-Translocon of Atypical Enteropathogenic Escherichia coli (aEPEC) Can Mediate Adherence. [PDF]
The intimin protein is the major adhesin involved in the intimate adherence of atypical enteropathogenic Escherichia coli (aEPEC) strains to epithelial cells, but little is known about the structures involved in their early colonization process. A previous study demonstrated that the type III secretion system (T3SS) plays an additional role in the ...
Santos FF +11 more
europepmc +9 more sources
Escherichia coli type III secretion system 2: a new kind of T3SS? [PDF]
Type III secretion systems (T3SSs) are employed by Gram-negative bacteria to deliver effector proteins into the cytoplasm of infected host cells. Enteropathogenic Escherichia coli use a T3SS to deliver effector proteins that result in the creation of the attaching and effacing lesions.
Zhou, Mingxu +4 more
openaire +4 more sources
The pathogenicity factor HrpF interacts with HrpA and HrpG to modulate type III secretion system (T3SS) function and t3ss expression in Pseudomonas syringae pv. averrhoi [PDF]
Summary To ensure the optimal infectivity on contact with host cells, pathogenic Pseudomonas syringae has evolved a complex mechanism to control the expression and construction of the functional type III secretion system (T3SS) that serves as a dominant pathogenicity factor.
Yi-Chiao, Huang +4 more
openaire +3 more sources
The MinCDE Cell Division System Participates in the Regulation of Type III Secretion System (T3SS) Genes, Bacterial Virulence, and Motility in Xanthomonas oryzae pv. oryzae. [PDF]
Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial leaf blight (BLB) in rice, which is one of the most severe bacterial diseases in rice in some Asian countries. The type III secretion system (T3SS) of Xoo encoded by the hypersensitive response and pathogenicity (hrp) genes is essential for its pathogenicity in host rice.
Yan Y +6 more
europepmc +4 more sources
Small-Molecule Inhibitors of the Type III Secretion System
Drug-resistant pathogens have presented increasing challenges to the discovery and development of new antibacterial agents. The type III secretion system (T3SS), existing in bacterial chromosomes or plasmids, is one of the most complicated protein ...
Lingling Gu +4 more
doaj +2 more sources
The Type III Secretion System (T3SS) is a Determinant for Rice-Endophyte Colonization by Non-Photosynthetic Bradyrhizobium. [PDF]
Plant associations by bradyrhizobia have been detected not only in leguminous plants, but also in non-leguminous species including rice. Bradyrhizobium sp. SUTN9-2 was isolated from Aeschynomene americana L., which is a leguminous weed found in the rice fields of Thailand. This strain promoted the highest total rice (Oryza sativa L.
Piromyou P +9 more
europepmc +4 more sources
The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus. [PDF]
AbstractLarge‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates ...
Zhang YY +15 more
europepmc +4 more sources

