Results 11 to 20 of about 373,461 (150)
Recruitment of heterologous substrates by bacterial secretion systems for transkingdom translocation
Bacterial secretion systems mediate the selective exchange of macromolecules between bacteria and their environment, playing a pivotal role in processes such as horizontal gene transfer or virulence.
Dolores L. Guzmán-Herrador +2 more
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Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic airway infection in bronchiectasis patients and is closely associated with poor prognosis.
Liu Yanan +7 more
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Primary architecture and energy requirements of Type III and Type IV secretion systems
Many pathogens use Type III and Type IV protein secretion systems to secrete virulence factors from the bacterial cytosol into host cells. These systems operate through a one-step mechanism. The secreted substrates (protein or nucleo-protein complexes in
Elena Cabezón +2 more
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Analysis of the expression, secretion and translocation of the Salmonella enterica type III secretion system effector SteA. [PDF]
Many Gram-negative pathogens possess virulence-related type III secretion systems. Salmonella enterica uses two of these systems, encoded on the pathogenicity islands SPI-1 and SPI-2, respectively, to translocate more than 30 effector proteins into ...
Elena Cardenal-Muñoz +1 more
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ATPase-independent type-III protein secretion in Salmonella enterica. [PDF]
Type-III protein secretion systems are utilized by gram-negative pathogens to secrete building blocks of the bacterial flagellum, virulence effectors from the cytoplasm into host cells, and structural subunits of the needle complex.
Marc Erhardt +3 more
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Infections caused by Gram-negative pathogens pose a major health burden. Both respiratory and gastrointestinal infections are commonly associated with these pathogens.
Nadja Blasey +3 more
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The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence
Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert +7 more
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The Gram-negative bacterium Pseudomonas plecoglossicida has caused visceral granulomas disease in several farmed fish species, including large yellow croaker (Larimichthys crocea), which results in severe economic losses. Type III secretion systems (T3SS)
Pan Qin +8 more
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Current methods for screening small molecules that inhibit the plasmid pCD1-encoded Yersinia pestis type III secretion system (T3SS) include lengthy growth curves followed by multistep luminescence assays or Western blot assays to detect secretion, or ...
Sukriti Prashar +8 more
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The secretion of bacterial virulence factors and flagellar components requires the assistance of specific type III and flagellar chaperones. Standard computational annotation of the genome of Xanthomonas axonopodis pv citri, a plant pathogen that causes ...
Letícia Khater +5 more
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