Results 11 to 20 of about 373,461 (150)

Recruitment of heterologous substrates by bacterial secretion systems for transkingdom translocation

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Bacterial secretion systems mediate the selective exchange of macromolecules between bacteria and their environment, playing a pivotal role in processes such as horizontal gene transfer or virulence.
Dolores L. Guzmán-Herrador   +2 more
doaj   +1 more source

A truncated mutation of MucA in Pseudomonas aeruginosa from a bronchiectasis patient affects T3SS expression and inflammasome activation

open access: yesActa Biochimica et Biophysica Sinica, 2022
Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic airway infection in bronchiectasis patients and is closely associated with poor prognosis.
Liu Yanan   +7 more
doaj   +1 more source

Primary architecture and energy requirements of Type III and Type IV secretion systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Many pathogens use Type III and Type IV protein secretion systems to secrete virulence factors from the bacterial cytosol into host cells. These systems operate through a one-step mechanism. The secreted substrates (protein or nucleo-protein complexes in
Elena Cabezón   +2 more
doaj   +1 more source

Analysis of the expression, secretion and translocation of the Salmonella enterica type III secretion system effector SteA. [PDF]

open access: yesPLoS ONE, 2011
Many Gram-negative pathogens possess virulence-related type III secretion systems. Salmonella enterica uses two of these systems, encoded on the pathogenicity islands SPI-1 and SPI-2, respectively, to translocate more than 30 effector proteins into ...
Elena Cardenal-Muñoz   +1 more
doaj   +1 more source

ATPase-independent type-III protein secretion in Salmonella enterica. [PDF]

open access: yesPLoS Genetics, 2014
Type-III protein secretion systems are utilized by gram-negative pathogens to secrete building blocks of the bacterial flagellum, virulence effectors from the cytoplasm into host cells, and structural subunits of the needle complex.
Marc Erhardt   +3 more
doaj   +1 more source

Targeting bacterial pathogenesis by inhibiting virulence-associated Type III and Type IV secretion systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Infections caused by Gram-negative pathogens pose a major health burden. Both respiratory and gastrointestinal infections are commonly associated with these pathogens.
Nadja Blasey   +3 more
doaj   +1 more source

The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence

open access: yesBiomolecules, 2023
Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert   +7 more
doaj   +1 more source

Comparative secretome analysis reveals cross-talk between type III secretion system and flagella assembly in Pseudomonas plecoglossicida

open access: yesHeliyon, 2023
The Gram-negative bacterium Pseudomonas plecoglossicida has caused visceral granulomas disease in several farmed fish species, including large yellow croaker (Larimichthys crocea), which results in severe economic losses. Type III secretion systems (T3SS)
Pan Qin   +8 more
doaj   +1 more source

Novel Disk Diffusion Assay on Magnesium Oxalate Agar To Evaluate the Susceptibility of Yersinia pestis to Type III Secretion System Inhibitors

open access: yesMicrobiology Spectrum, 2021
Current methods for screening small molecules that inhibit the plasmid pCD1-encoded Yersinia pestis type III secretion system (T3SS) include lengthy growth curves followed by multistep luminescence assays or Western blot assays to detect secretion, or ...
Sukriti Prashar   +8 more
doaj   +1 more source

In silico identification of potential chaperone genes that belong to type III and type IV secretion systems in Xanthomonas axonopodis pv citri

open access: yesGenetics and Molecular Biology, 2005
The secretion of bacterial virulence factors and flagellar components requires the assistance of specific type III and flagellar chaperones. Standard computational annotation of the genome of Xanthomonas axonopodis pv citri, a plant pathogen that causes ...
Letícia Khater   +5 more
doaj   +1 more source

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