Identifying indispensable proteins of the type III secretion systems of Salmonella enterica serovar Typhimurium strain LT2 [PDF]
Lahiri C +4 more
europepmc +2 more sources
Structure of HrcQ(B)-C, a conserved component of the bacterial type III secretion systems [PDF]
Type III secretion systems enable plant and animal bacterial pathogens to deliver virulence proteins into the cytosol of eukaryotic host cells, causing a broad spectrum of diseases including bacteremia, septicemia, typhoid fever, and bubonic plague in ...
A. P. Tampakaki +33 more
core +2 more sources
Type III secretion systems harbored by several Gram-negative bacteria are often used to deliver host-modulating effectors into infected eukaryotic cells. About 20 core proteins are needed for assembly of a secretion apparatus.
Jyoti M. Gurung +11 more
doaj +1 more source
Electron Cryotomography of Bacterial Secretion Systems [PDF]
In biology, function arises from form. For bacterial secretion systems, which often span two membranes, avidly bind to the cell wall, and contain hundreds of individual proteins, studying form is a daunting task, made possible by electron cryotomography (
Abendroth +72 more
core +1 more source
Transposon mutagenesis was used to isolate nonpathogenic mutants of Xanthomonas campestris pv. glycines 8ra, which causes bacterial pustule disease in soybean.
Changsik Oh +3 more
doaj +1 more source
SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system [PDF]
Bacterial pathogens use horizontal gene transfer to acquire virulence factors that influence host colonization, alter virulence traits, and ultimately shape the outcome of disease following infection.
K. Coombes, Brian +8 more
core +1 more source
Type III Secretion Effectors with Arginine N-Glycosyltransferase Activity [PDF]
Type III secretion systems are used by many Gram-negative bacterial pathogens to inject proteins, known as effectors, into the cytosol of host cells. These virulence factors interfere with a diverse array of host signal transduction pathways and cellular
Araujo Garrido, Juan Luis +2 more
core +1 more source
Patterns of expression and translocation of the ubiquitin ligase SlrP in Salmonella enterica serovar typhimurium. [PDF]
SlrP is an E3 ubiquitin ligase that can be translocated into eukaryotic host cells by the two type III secretion systems that are expressed by Salmonella enterica serovar Typhimurium and are encoded in Salmonella pathogenicity islands 1 (SPI1) and 2 ...
Cordero Alba, Mar +1 more
core +1 more source
Structure of the type III secretion effector protein ExoU in complex with its chaperone SpcU. [PDF]
Disease causing bacteria often manipulate host cells in a way that facilitates the infectious process. Many pathogenic gram-negative bacteria accomplish this by using type III secretion systems.
Andrei S Halavaty +8 more
doaj +1 more source
SrfJ, a salmonella type III secretion system effector regulated by PhoP, RcsB, and IolR. [PDF]
Virulence-related type III secretion systems are present in many Gram-negative bacterial pathogens. These complex devices translocate proteins, called effectors, from the bacterium into the eukaryotic host cell. Here, we identify the product of srfJ, a
Bernal Bayard, Joaquín +2 more
core +1 more source

