Results 31 to 40 of about 33,313 (146)

Structural biology of type VI secretion systems. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2012
Type VI secretion systems (T6SSs) are transenvelope complexes specialized in the transport of proteins or domains directly into target cells. These systems are versatile as they can target either eukaryotic host cells and therefore modulate the bacteria–host interaction and pathogenesis or bacterial cells and therefore facilitate access to a specific ...
Cascales E, Cambillau C.
europepmc   +7 more sources

Adaptor Proteins of Type VI Secretion System Effectors [PDF]

open access: yesTrends in Microbiology, 2017
Bacteria use the type VI secretion system (T6SS) to kill neighboring cells. One key feature of the T6SS is the secretion of diverse effectors. Here, we discuss six publications that describe three superfamilies of T6SS proteins, each dedicated to mediate the secretion of cognate effectors.
Unterweger, D, Kostiuk, B, Pukatzki, S
openaire   +2 more sources

Type VI Secretion System Helps Find a Niche [PDF]

open access: yesCell Host & Microbe, 2014
Type VI secretion systems (T6SSs) deliver toxins into target cells and thus play a role in bacterial warfare. In this issue of Cell Host & Microbe, Ma et al. (2014) demonstrate that T6SS-dependent attack during interbacterial competition in the host context enables niche colonization by Agrobacterium tumefaciens.
Kapitein, Nicole, Mogk, Axel
openaire   +2 more sources

Integrating signals to drive type VI secretion system killing [PDF]

open access: yesEnvironmental Microbiology, 2020
Ministerio de Ciencia, Innovación y Universidades RTI2018-096936-J ...
Patricia Bernal   +2 more
openaire   +4 more sources

Comparative Genomics of Aeromonas hydrophila Secretion Systems and Mutational Analysis of hcp1 and vgrG1 Genes From T6SS

open access: yesFrontiers in Microbiology, 2019
Virulent Aeromonas hydrophila causes severe motile Aeromonas septicemia in warmwater fishes. In recent years, channel catfish farming in the U.S.A. and carp farming in China have been affected by virulent A.
Hasan C. Tekedar   +5 more
doaj   +1 more source

Bacterial type VI secretion system facilitates niche domination [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
Over the last few decades humanity has experienced a series of tremendous technological advances, especially in the realm of basic science. A plethora of new approaches has allowed us to appreciate life in previously unimaginable detail, prompting the realization that life in the microscopic world is not so different from what we can observe with our ...
Drebes Dörr, Natália C.   +1 more
openaire   +2 more sources

Phage tail-like particles are versatile bacterial nanomachines – A mini-review

open access: yesJournal of Advanced Research, 2019
Type VI secretion systems and tailocins, two bacterial phage tail-like particles, have been reported to foster interbacterial competition. Both nanostructures enable their producer to kill other bacteria competing for the same ecological niche ...
Sascha Patz   +6 more
doaj   +1 more source

Structure of the Type VI Secretion System Contractile Sheath [PDF]

open access: yesCell, 2015
Bacteria use rapid contraction of a long sheath of the type VI secretion system (T6SS) to deliver effectors into a target cell. Here, we present an atomic-resolution structure of a native contracted Vibrio cholerae sheath determined by cryo-electron microscopy. The sheath subunits, composed of tightly interacting proteins VipA and VipB, assemble into a
Kudryashev, Mikhail   +9 more
openaire   +4 more sources

Diversification of the Type VI Secretion System in Agrobacteria

open access: yesmBio, 2021
The T6SS is used by several taxa of Gram-negative bacteria to secrete toxic effector proteins to attack others. Diversification of effector collections shapes bacterial interactions and impacts the health of hosts and ecosystems in which bacteria reside.
Chih-Feng Wu   +7 more
openaire   +3 more sources

Analysis of the outer membrane proteome and secretome of Bacteroides fragilis reveals a multiplicity of secretion mechanisms. [PDF]

open access: yesPLoS ONE, 2015
Bacteroides fragilis is a widely distributed member of the human gut microbiome and an opportunistic pathogen. Cell surface molecules produced by this organism likely play important roles in colonization, communication with other microbes, and ...
Marlena M Wilson   +2 more
doaj   +1 more source

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