Results 241 to 250 of about 7,552,757 (287)

Type VII collagen is a component of cylindroma basement membrane zone

Journal of Cutaneous Pathology, 1989
Cylindroma basement membranes (BMs) were studied by electron microscopy and immunofluorescence with antibodies to Types IV and VII collagen in order to correlate the ultrastructure with the biochemical characteristics. Type IV collagen served as a marker for lamina densa structures and Type VII collagen for the anchoring fibrils. Ultrastructurally, the
Pfaltz M, Bruckner-Tuderman L, Schnyder UW   +2 more
openaire   +4 more sources

Immune reactivity to type VII collagen: implications for gene therapy of recessive dystrophic epidermolysis bullosa

Gene Therapy, 2010
International audienceRecessive dystrophic epidermolysis bullosa (RDEB) is a severe genodermatosis caused by loss-of-function mutations in COL7A1 encoding type VII collagen, the component of anchoring fibrils.
Matthias Titeux, Jose E Mejia, Catherine Prost-Squarcioni   +2 more
exaly   +2 more sources

Type VII Collagen in the Human Accommodation System: Expression in Ciliary Body, Zonules, and Lens Capsule [PDF]

Investigative Ophthalmology and Visual Science, 2018
To investigate intraocular expression of COL7A1 and its protein product type VII collagen, particularly at the accommodation system. Eyes from 26 human adult donors were used.
Bart Wullink, Hendri H. Pas, Leonoor Los
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Molecular cloning and characterization of type VII collagen cDNA

Biochemical and Biophysical Research Communications, 1992
Type VII collagen, located in human epidermal basement membrane, is the primary pathogenic target molecule in epidermolysis bullosa acquisita and epidermolysis bullosa dystrophica. Using a monoclonal antibody against the non-collagenous domain of type VII collagen, approximately 1 Kb cDNA was isolated from human keratinocyte library.
T, Tanaka, K, Takahashi, F, Furukawa, S, Imamura   +3 more
openaire   +2 more sources

Distribution of type-VII collagen in xenografted human carcinomas

Cell & Tissue Research, 1993
The distribution of type-VII collagen, the main molecular component of the anchoring fibrils (AF) attaching the basal lamina (BL, lamina densa of the basement membrane) to the surrounding connective tissue, was investigated in four xenografted human carcinomas of the hypopharynx (H-Stg 1), the lung (L 261), the sigmoid colon (CA 1), and the rectum (R ...
P, Köpf-Maier, C, Schröter-Kermani
openaire   +2 more sources

Laminins, tenascin and type VII collagen in colorectal mucosa

The Histochemical Journal, 1996
The distribution of different laminin polypeptides, type VII collagen and tenascin has been studied in adult and foetal colorectal mucosa by using the indirect immunofluorescence technique. Immunoreactivity for laminin alpha 1 chain was located to basement membranes of epithelia, muscularis mucosae, and blood vessels, respectively in different segments
J, Lohi, I, Leivo, T, Tani, T, Kiviluoto, E, Kivilaakso, R E, Burgeson, I, Virtanen   +6 more
openaire   +2 more sources

Abnormal deposition of type VII collagen in Kindler syndrome

Archives of Dermatological Research, 1999
Kindler syndrome is an extremely rare genetic disorder with features of epidermolysis bullosa and poikiloderma congenitale. Approximately 70 cases have been documented in the past 50 years, but only a few investigations of the basement membrane components have been done on these patients.
C B, Wiebe, H S, Larjava
openaire   +2 more sources

Autoimmunity to Type VII Collagen: Epidermolysis Bullosa Acquisita

Clinical Reviews in Allergy & Immunology, 2007
Epidermolysis bullosa acquisita (EBA) is an acquired, autoimmune, mechanobullous disease with clinical features reminiscent of genetic dystrophic epidermolysis bullosa (DEB). EBA patients have skin fragility, blisters, scars, and milia formation. DEB is due to a genetic defect in the gene-encoding type VII collagen, which makes anchoring fibrils ...
David T, Woodley, Jennifer, Remington, Mei, Chen   +2 more
openaire   +2 more sources

The epitope for anti-type VII collagen monoclonal antibody (LH7:2) locates at the central region of the N-terminal non-collagenous domain of type VII collagen

British Journal of Dermatology, 2006
The monoclonal antibody LH7:2, which recognizes type VII collagen, is now used in the diagnosis and prenatal diagnosis of epidermolysis bullosa dystrophica. We constructed the expression vector which contains the cDNA fragment of type VII collagen. Western blot with LH7:2 was carried out with the resultant fusion proteins which overlap each other, and ...
T, Tanaka, K, Takahashi, F, Furukawa, S, Imamura   +3 more
openaire   +2 more sources

Autoimmunity to Type VII Collagen: Epidermolysis Bullosa Acquisita

2008
Epidermolysis bullosa acquisita (EBA) is an acquired, mechanobullous disease characterized by autoimmunity to type VII collagen. Type VII collagen makes anchoring fibrils, structures that connect the epidermis and its underlying basement membrane zone to the papillary dermis.
Jennifer, Remington, Mei, Chen, Julie, Burnett, David T, Woodley   +3 more
openaire   +2 more sources