Results 111 to 120 of about 40,608 (276)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Catalyzed Deposition of Signal Reporter for Highly Sensitive Surface-Enhanced Raman Spectroscopy Immunoassay Based on Tyramine Signal Amplification Strategy.

open access: yesAnalytical Chemistry, 2018
A novel surface-enhanced Raman spectroscopy (SERS) sensor was proposed for an ultrasensitive detection immunoassay based on tyramine signal amplification (TSA) strategy.
Cuicui Fu   +5 more
semanticscholar   +1 more source

Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni   +12 more
wiley   +1 more source

Interaction of Cocaine and Tyramine on the Isolated Mammalian Heart [PDF]

open access: yes, 1963
Cocaine added to the fluid perfusing the isolated guinea-pig heart antagonised the action of tyramine in reducing the noradrenaline content of the heart.
J B Farmer, B Petch
core   +1 more source

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal   +10 more
wiley   +1 more source

Sustainable production of the drug precursor tyramine by engineered Corynebacterium glutamicum [PDF]

open access: yes
Poethe S-S, Junker N, Meyer F, Wendisch VF. Sustainable production of the drug precursor tyramine by engineered Corynebacterium glutamicum. Applied Microbiology and Biotechnology.
Meyer, Florian ; https://orcid.org/   +3 more
core   +1 more source

Administration of Supplemental L-Tyrosine with Phenelzine: a Clinical Literature Review [Retraction]

open access: yesClinical Pharmacology: Advances and Applications, 2021
Hinz M, Stein A, Cole T, Ryan P. Clin Pharmacol. 2014;6:107–110.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This review article cites several original ...
Hinz M, Stein A, Cole T, Ryan P
doaj  

TYRAMINE REVEALS FAILING α2-ADRENOCEPTOR CONTROL OF CATECHOLAMINE RELEASE AND TOTAL PERIPEHRAL VASCULAR RESISTANCE IN HYPERTENSIVE RATS

open access: yesFrontiers in Neurology, 2013
α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension.
Torill eBerg, Jørgen eJensen
doaj   +1 more source

Effects of Exogenous Monosodium Glutamate on GABA Accumulation and Volatile/Nonvolatile Metabolites in Black Highland Barley

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
wiley   +1 more source

Identification of tyramine and octopamine in human serum by mass fragmentography [PDF]

open access: yes, 1977
Tyramine and octopamine were identified by means of mass fragmentography in human serum. The peaks identical to the retention time of tyramine and octopamine were found on gaschromatogram obtained from serum sample.
Okita, Misako, Misako OKITA
core   +1 more source

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