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Mutagenic products are promoted in the nitrosation of tyramine [PDF]

Food Chemistry, 2017
Tyramine is a biogenic compound derived from the decarboxylation of the amino acid tyrosine, and is therefore present at important concentrations in a broad range of raw and fermented foods.
Mario Gonzalez-Jimenez, Emilio Calle, J Casado   +2 more
exaly   +2 more sources

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Dietary Migraine and Tyramine Metabolism

Nature, 1971
MIGRAINE afflicts some 10–15% of the population, which includes a subgroup of dietary migraine sufferers, all of whom specifically exclude certain foods from their diet. When Hanington1 studied this group extensively all subjects reacted adversely to chemically pure tyramine.
I, Smith, A H, Kellow, P E, Mullen, E, Hanington   +3 more
openaire   +2 more sources

Tyramine content of some cheeses

Toxicology and Applied Pharmacology, 1970
Abstract The tyramine content of various cheeses used in Turkey and some surrounding countries was determined using a spectrofluorimetric method. The highest amount of tyramine was found in tulum cheese (207 ± 16.1 μg/g) and the lowest in white cheese (17.5 ± 6.1 μg/g). These results were on the whole in line with those of previous work regarding the
S O, Kayaalp, N, Renda, S, Kaymakcalan, A, Ozer   +3 more
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Uptake of tyramine by rat hepatocytes

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1993
Observations on the uptake of tyramine by hepatocytes indicate that the amine is taken up by simple diffusion and a transporter mediated system, with a Km of 39 microM and a Vmax of 270 pmol/min/10(5) cells. The carrier-mediated process is pH- and temperature-dependent and requires an activation energy of 12.9 kcal/mol.
Z D, Zhong, S, Wattiaux-De Coninck, R, Wattiaux   +2 more
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Failure of tyramine to induce migraine

Neurology, 1977
In a double-blind study of 80 migraine patients, headache was precipitated by ingestion of 200 mg tyramine and not by placebo in eight individuals, but retesting of seven of these patients did not produce the same results. Placebo produced as severe headache as tyramine and in an even larger number of patients.
D K, Ziegler, R, Stewart
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Thermoregulatory responses to tyramine in the pigeon

Acta Physiologica Scandinavica, 1980
Intravenous injections of different doses of tyramine induced hypothermia in the pigeon in the cold and a moderate hyperthermia in the warm environment. The hypothermia was correlated with a dose‐dependent decline in shivering. Hyperthermia was attributed to the chrono‐ and inotropic effects of tyramine.
R, Hissa, J C, George, E D, Stevens, S, Saarela   +3 more
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The uptake of tyramine by rat platelets

Biochemical Pharmacology, 1981
Abstract The uptake of [ 14 Cityramine by rat platelets was less efficient than the uptake of [ 14 C]-5-HT. [ 14 C]-Tyramine was taken up in a two phase curve which could be resolved into a rapid saturable phase and a slower non-saturable phase that was linear with concentration.
L, Bianchi, L, Stella, G, Dagnino, G, de Gaetano, E C, Rossi   +4 more
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MECHANISMS OF THE PHOTOSENSITIZED OXIDATION OF TYRAMINE

Photochemistry and Photobiology, 1977
Abstract— …According to the criteria of enhancement in D2O and inhibition by sodium azide, the oxidation of tyramine photosensitized by methylene blue is largely a singlet oxygen or Type II process. Its quantum yield approximates 0.3 in D2O at pH 10. There is a less efficient reaction not quenched by azide, which is assigned to a dye‐substrate or Type ...
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The tyramine conjugation test and depression

Acta Neuropsychiatrica, 1990
SummaryIn this article the value of the tyramine conjugation test (TCT) as a predictor of the response to antidepressive medication is reviewed. The TCT seems of little discomfort for the patient, is easy to perform and is suggested to have a high sensitivity and specificity. In addition, there are indications that a decreased tyamine conjugation could
J G, Storosum, F, de Jonghe, H F, Schalken, J, Huyser, H N, Sno   +4 more
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MIGRAINE, TYRAMINE AND BLOOD SEROTONIN

Headache: The Journal of Head and Face Pain, 1976
SYNOPSIS Whole blood serotonin levels and headache symptoms were studied in 26 migrainous patients during a three day period with administration of tyramine the first day, reserpine the second day.
Dewey K. Ziegler, Ruth Stephenson Hassanein, Daniel F. Ward   +2 more
openaire   +2 more sources