Results 91 to 100 of about 53,271 (260)

JI‐CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7‐H3

open access: yesCancer Science, EarlyView.
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee   +4 more
wiley   +1 more source

Extraction optimization, antioxidant activity, and tyrosinase inhibitory capacity of polyphenols from Lonicera japonica

open access: yesFood Science & Nutrition, 2019
The objective of this research was twofold: first, to optimize the extraction process of Lonicera japonica polyphenols using a response surface methodology, and second, to study the antioxidant activity and tyrosinase inhibitory capacity of the ...
ZiLuan Fan   +7 more
semanticscholar   +1 more source

Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis

open access: yesJournal of Lipid Research, 1999
The purpose of this study was to investigate the mechanism of fatty acid-induced regulation of melanogenesis. An apparent regulatory effect on melanogenesis was observed when cultured B16F10 melanoma cells were incubated with fatty acids, i.e., linoleic ...
Hideya Ando   +8 more
doaj   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh   +5 more
wiley   +1 more source

Anti-Melanogenic Effects of Flavonoid Glycosides from Limonium tetragonum (Thunb.) Bullock via Inhibition of Tyrosinase and Tyrosinase-Related Proteins

open access: yesMolecules, 2017
Overproduction and stimulation of tyrosinase result in increased melanogenesis of which several skin disorders such as freckles, spots, and hyperpigmentation appear as complications.
Seul-Gi Lee   +3 more
doaj   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang   +7 more
wiley   +1 more source

DcH3.3 and DcNAC1 Regulate the Expression of UGT73A93 Involved in the Changes in Flower Colour and Fungal Resistance in Carnation

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Carnation (Dianthus caryophyllus) contains abundant flavonoid glycosides (FGs), which are important natural functional and colour components. However, there are few reports on the modification of UDP‐glycosyltransferases (UGTs) in relation to flavonoids in carnation.
Xuhong Zhou   +6 more
wiley   +1 more source

Advances in organic UV filters for sunscreens over the past decade

open access: yesPhotochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon   +4 more
wiley   +1 more source

Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles

open access: yesDrug Design, Development and Therapy, 2015
Hwi Young Yun,1 Do Hyun Kim,1 Sujin Son,1 Sultan Ullah,1 Seong Jin Kim,1 Yeon-Jeong Kim,2 Jin-Wook Yoo,1 Yunjin Jung,1 Pusoon Chun,2 Hyung Ryong Moon1 1College of Pharmacy, Pusan National University, Busan, 2College of Pharmacy, Inje University, Gimhae,
Yun HY   +9 more
doaj  

Patchouli Alcohol: A Potent Tyrosinase Inhibitor Derived from Patchouli Essential Oil with Potential in the Development of a Skin-Lightening Agent

open access: yesCosmetics
The inhibitory effects of Pogostemon cablin essential oil (patchouli essential oil, PEO) and its primary bioactive compound, patchouli alcohol (PA), on tyrosinase and melanin were investigated in vitro and ex vivo. Treatment with PEO and PA significantly,
K. J. Senthil Kumar   +4 more
doaj   +1 more source

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