Results 91 to 100 of about 45,442 (272)
Brain Pathology, EarlyView.Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
wiley +1 more source
Shipin yu jixieObjective: This study aimed to develop new, efficient, safe and precise tyrosinase inhibitors. Methods: The orthogonal test was used to optimize the extraction conditions of kojic acid.
FANG Jingjie +3 more
doaj +1 more source
DMPB increases tyrosinase expression but not tyrosinase activity.
, 2015 (A) B16F10 cells were treated with 30 μM of DMPB for 48 hr, and mRNA level of tyrosinase was analyzed by RT-PCR (top panel). Total cell lysate was extracted and tyrosinase levels were measured by Western blot analysis.
Seung Hyun Bang (735171) +7 more
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Enzymes in Ontogenesis (orthoptera): I. Tyrosinase [PDF]
, 1935 Variations in concentration of tyrosinase throughout the entire embryonic development of the grasshopper, Melanoplus differentialis, have been determined by measuring the oxygen uptake of the tyrosinase-tyrosine reaction with the Barcroft-Warburg ...
Bodine, J. H., Boell, E. J.
core +1 more source
Cosmetics, 2017 Many active cosmetic ingredients formulated as medicated whitening products (quasi-drugs) achieve their effect through inhibition of tyrosinase activity, but no products can achieve this effect through degradation of intramelanosomal tyrosinase.
Haifeng Zeng +6 more
doaj +1 more source
Studies on Inhibition of Tyrosinase
Experimental Biology and Medicine, 1954 SummaryUsing a previously described spot-spray technic, more than 400 simple, aromatic compounds were investigated as inhibitors of tyrosinase. 4-Chlororesorcinol inhibited melanin formation from tyrosine, DOPA or epinephrine at a concentration of 10-9; it was thus 20,000 times more potent than resorcinol.
F C, KULL, M R, GRIMM, R L, MAYER
openaire +2 more sources
, 2014 Hydroquinone (HQ) is used as a depigmenting agent. In this work we demonstrate that tyrosinase hydroxylates HQ to 2-hydroxyhydroquinone (HHQ). Oxy-tyrosinase hydroxylates HQ to HHQ forming the complex met-tyrosinase-HHQ, which can evolve in two different
Rodriguez-López, José Neptuno +6 more
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Bakuchiol: From structural mimicry to systems‐level skin biology
International Journal of Cosmetic Science, EarlyView.Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
MoleculesCannabidiol (CBD), a non-psychoactive cannabinoid, has attracted significant research interest due to its antioxidant, anti-inflammatory, and neuroprotective properties.
Eliav Peretz, Noa Ashkenazi, Sanaa Musa
doaj +1 more source