Results 161 to 170 of about 45,442 (272)

Chlorine Position Governs the Multitarget Bioactivity of Phenylhydrazines: In Vitro Antioxidant, Anti‐Inflammatory, Anti‐Tyrosinase and Antibacterial Evaluation Supported by DFT and Molecular Docking

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
Positional chlorination emerges as a key determinant of multitarget activity in phenylhydrazines. The para‐chloro derivative H3 shows the strongest anti‐inflammatory response, notable antibacterial activity, favorable ADMET behavior, and high COX‐2 affinity. DFT descriptors and molecular docking rationalize these substitution‐dependent effects, linking
L. Aouachria, S. Issadi, H. Debab, I. Selatnia, A.G. Soliman, K. Metwally, O. M. A. Khamaysa, Han‐seung Lee, Hassane Lgaz   +8 more
wiley   +1 more source

Inhibition effects and binding interactions of epigallocatechin and gallocatechin on tyrosinase and their anti-melanogenesis activity. [PDF]

J Enzyme Inhib Med Chem
Zhang J, Shi Z, Li J, Li K, Wu F, Zhao M, Xie R, Luo H.   +7 more
europepmc   +1 more source

Synthesis of Methylisoxazol‐5(4H)‐One Derivatives Using an ʟ‐Proline‐Functionalized‐MMT Catalyst: Molecular Docking and Cancer Cell Line Cytotoxicity Studies

ChemistrySelect, Volume 11, Issue 38, 13 October 2026.
An efficient and sustainable method for the synthesis of biologically relevant isoxazoles is developed using modified montmorillonite‐K10 (MMT) nanoclay as a heterogeneous catalyst. The catalyst exhibited good stability and reusability over five cycles, with minimal loss of activity (95%–88%). ABSTRACT Guided by green chemistry principles, an efficient
Anushka Servesh, Santhosh Govindaraju, Sumaiya Tabassum, Sankar Ganesh Ramaraj   +3 more
wiley   +1 more source

Evidence for a Role of Hox2 in Atrial Siphon Fusion of the Ascidian Ciona

Development, Growth &Differentiation, Volume 68, Issue 8, October 2026.
ABSTRACT The hallmark of sessile adult ascidians is a vase‐like shape with a single oral and atrial siphon. Ciona, however, develops two atrial siphons after metamorphosis, which subsequently fuse into one. The mechanisms underlying this fusion are unknown. This study suggests that Hox2 controls this process.
Yurong Liu, Keita Yoshida, Akiko Hozumi, Kosuke Itagaki, Nicholas Treen, Tetsushi Sakuma, Takashi Yamamoto, Toshinori Endo, Yasunori Sasakura   +8 more
wiley   +1 more source

Structural Dynamics and Susceptibility of Aminonaphthoquinone-Chalcone Hybrids Against Human Tyrosinase. [PDF]

Int J Mol Sci
Sabuakham S, Nuramrum N, Rungrotmongkol T, Pingaew R, Mahalapbutr P.   +4 more
europepmc   +1 more source

The Tyrosinase-Tyrosine Reaction [PDF]

Biochemical Journal, 1926
openaire   +4 more sources

The action of tyrosinase on monophenols [PDF]

Biochemical Journal, 1949
openaire   +2 more sources

Plant‐Derived Senolytic Ingredient, Camellia sinensis Root Extract, Ameliorates Skin Aging‐Associated Phenotypes

Experimental Dermatology, Volume 35, Issue 10, October 2026.
Camellia sinensis root extract (SENOMUNE) preferentially reduced senescent dermal fibroblast viability and decreased SASP‐associated factor expression and secretion. Its effects were associated with features consistent with LMP/cathepsin/AIF‐associated caspase‐independent cell death.
Sunyoung Park, Siyoung Cho, Daejin Min, Hyunjung Choi, Kyeonghwan Hwang, In Sup Kil, Won‐Seok Park, Hyoung‐June Kim   +7 more
wiley   +1 more source

Enhancement of Anti-Melanogenic Activity of <i>Pinctada martensii</i> Nacre-Derived Peptide Through <i>C</i>-Terminal Amidation: Mechanism Investigation in B16F10 Cells. [PDF]

Mar Drugs
Lin H, Chang R, Li F, Gao J, Chen Z, Liang Y, Cao W, Zheng H.   +7 more
europepmc   +1 more source

The nature of the action of tyrosinase [PDF]

Biochemical Journal, 1934
openaire   +2 more sources