Results 171 to 180 of about 45,442 (272)

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

open access: yesInternational Journal of Cosmetic Science, Volume 48, Issue 5, Page 1006-1017, October 2026.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang   +7 more
wiley   +1 more source

Antioxidant Activity of Heated Radish (<i>Raphanus sativus</i> L.) and Tyrosinase Inhibition. [PDF]

open access: yesPrev Nutr Food Sci
Jo YJ   +6 more
europepmc   +1 more source

Truffle thio-flavours reversibly inhibit truffle tyrosinase

open access: yes, 2003
Tyrosinase is an enzyme having two copper atoms at the reactive site occurring in prokaryotic and eukaryotic organisms. In animals tyrosinase is responsible for pigmentation, in plants for protection of injured tissues or, as in fungi, to harden cell ...
CESARE, Patrizia   +5 more
core  

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

open access: yesInternational Journal of Dermatology, Volume 65, Issue 10, Page 2038-2048, October 2026.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad   +2 more
wiley   +1 more source

Clinical Efficacy and Mechanisms of ZiyuShuang, an Anti‐Skin Aging Formula Identified Through Network Medicine Framework Analysis

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin aging, a key aspect of physiological decline, markedly affects appearance, making strategies to delay it vital for quality of life. Materials and Methods We applied network medicine analysis to screen herbal medicines from the TCMSP database, yielding an anti‐skin aging formula, ZiYuShuang (ZYS).
Yingpeng Tong   +6 more
wiley   +1 more source

Glucuronyl Glucosyloleanolate: A Safe and Potent AI‐Discovered Depigmenting Saponin

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Purpose Saponins are amphiphilic glycosides found in plants. They have long been used in traditional Asian remedies for their anti‐inflammatory, protective, and rejuvenating properties. One representative, Glucuronyl Glucosyloleanolate (GGO), was recently discovered using a combination of artificial intelligence and experimental testing as a ...
Yannick Quesnel, Michael Gold
wiley   +1 more source

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