Results 51 to 60 of about 39,961 (248)

Purification and Determination of the Chemical Structure of the Tyrosinase Inhibitor Produced by Trichoderma viride Strain H1-7 from a Marine Environment

open access: yes, 2008
Tyrosinase is a key enzyme in the synthesis of melanin and is widely distributed in animals, plants, and microorganisms. As excessive melanin production causes not only hyperpigmenting effects on human skin but also melanosis in various foods, an ...
Miyamoto, Katsuhiro   +17 more
core   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

A Simulation Study of Inhibition Assay With Theophylline on the Enzymatic Hydrolysis of p‐Nitrophenyl Phosphate With Alkaline Phosphatase in a Continuous Mode of Electrophoretically Mediated Microanalysis

open access: yesELECTROPHORESIS, EarlyView.
Inhibition assays in in‐capillary continuous enzymatic reaction were simulated using a MATLAB matrix. The enzymatic hydrolysis of p‐nitrophenyl phosphate (S) with alkaline phosphatase (ALP) was adopted as a model enzymatic reaction, where theophylline (I) was used as a model inhibitor.
Toshio Takayanagi   +2 more
wiley   +1 more source

Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors [PDF]

open access: yesPeerJ, 2018
Targeting tyrosinase is considered to be an effective way to control the production of melanin. Tyrosinase inhibitor is anticipated to provide new therapy to prevent skin pigmentation, melanoma and neurodegenerative diseases.
Qi Li   +7 more
doaj   +2 more sources

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

open access: yesFood Biomacromolecules, EarlyView.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li   +7 more
wiley   +1 more source

The Effect of Polyphenolic Extracts from 10 New Zealand Kiwifruit Cultivars in Inhibiting Tyrosinase Enzyme Activity

open access: yesNatural Product Communications
Objective The aim of this study was to assess the ability of polyphenolic extracts from different kiwifruit genotypes to affect tyrosinase enzyme activity and determine potential relationships between tyrosinase inhibition and polyphenolic composition ...
Andrew M. Carroll   +5 more
doaj   +1 more source

Anti melanogenic effect of Croton roxburghii and Croton sublyratus leaves in α-MSH stimulated B16F10 cells

open access: yesJournal of Traditional and Complementary Medicine, 2019
Croton roxburghii and Croton sublyratus have been used as skin treatments in traditional medicine. The objective of the present study was to investigate the antimelanogenic effect of ethanol extracts of Croton roxburghii (CRE) and Croton sublyratus (CSE)
Moragot Chatatikun   +4 more
doaj   +1 more source

Immunomodulatory Effect of Tilapia (Oreochromis niloticus) Scale Gelatin Peptides in RAW264.7 Macrophages and Caenorhabditis elegans

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Currently, small‐molecular‐weight collagen peptides are a research hotspot in functional factor development due to their high bioavailability and diverse bioactivities. In this study, gelatin was extracted from tilapia (Oreochromis niloticus) scales by hot water extraction, followed by pepsin hydrolysis and ultrafiltration to obtain the < 3 ...
Ya‐ru Liu   +5 more
wiley   +1 more source

Identification of an Alkylhydroquinone from Rhus succedanea as an Inhibitor of Tyrosinase and Melanogenesis

open access: yes, 2009
The alkylhydroquinone 10'(Z)-heptadecenylhydroquinone [HQ17( 1)], isolated from the sap of the lacquer tree Rhus succedanea, was found to inhibit the activity of tyrosinase and to suppress melanin production in animal cells.
Chen, Yun-Ru; Chiou, Robin Y.-Y.; Lin, Ting-Yu; Huang, Cheng-Po; Tang, Wei-Chien; Chen, Shui-Tein; Lin, Shwu-Bin   +1 more
core   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

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