Results 31 to 40 of about 53,271 (260)

Tyrosinase inhibitors as melanoma sensitizers: Boosting therapeutic efficacy

Supramolecular Materials
Melanoma therapy faces critical challenges due to melanin-mediated resistance mechanisms. The use of tyrosinase inhibitors to suppress tyrosinase activity and reduce melanogenesis, thereby sensitizing melanoma cells, represents a highly promising ...
Yongsheng Li, Kan Yang, Luyang Zhao
doaj   +1 more source

Biochemical Properties of Tyrosinase from Aspergillus terreus and Penicillium copticola; Undecanoic Acid from Aspergillus flavus, an Endophyte of Moringa oleifera, Is a Novel Potent Tyrosinase Inhibitor

Molecules, 2021
Tyrosinase is a copper-containing monooxygenase catalyzing the O-hydroxylation of tyrosine to 3,4-dihydroxyphenylalanine then to dopaquinone that is profoundly involved in melanin synthesis in eukaryotes.
Hanaa Salah Maamoun, Gamal H. Rabie, Ibrahim Shaker, Bothaina A. Alaidaroos, Ashraf S. A. El-Sayed   +4 more
doaj   +1 more source

Inhibition mechanism investigation of quercetagetin as a potential tyrosinase inhibitor

Frontiers in Chemistry
Tyrosinase is one important rate limiting enzyme in melanin synthesis, directly affecting the melanin synthesis. Quercetagetin is one active ingredient from marigold.
Faliang Liang
doaj   +1 more source

Natural and Bioinspired Phenolic Compounds as Tyrosinase Inhibitors for the Treatment of Skin Hyperpigmentation: Recent Advances

Cosmetics, 2019
One of the most common approaches for control of skin pigmentation involves the inhibition of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis.
L. Panzella, A. Napolitano
semanticscholar   +1 more source

From Fish Scale Gelatin to Tyrosinase Inhibitor: A Novel Peptides Screening Approach Application

Frontiers in Nutrition, 2022
Bioaffinity ultrafiltration combined with LC-Orbitrap-MS/MS was applied for the first time to achieve rapid screening and identification of tyrosinase inhibitory peptides (TYIPs) from grass carp scale gelatin hydrolysates.
Zi-Zi Hu, Xiao-Mei Sha, Lu Zhang, Min-Jun Zha, Zong-Cai Tu, Zong-Cai Tu   +5 more
doaj   +1 more source

Inhibitory Effects of Caulerpa racemosa, Ulva intestinalis, and Lobophora challengeriae on Tyrosinase Activity and α-MSH-Induced Melanogenesis in B16F10 Melanoma Cells

Life, 2023
Melanogenesis involves a synthesis of melanin pigment and is regulated by tyrosinase. The addition of whitening agents with tyrosinase-inhibiting properties in cosmetics is becoming increasingly important.
Pradtana Choosuwan, Jantana Praiboon, Korawinwich Boonpisuttinant, Anirut Klomjit, Narongrit Muangmai, Rapeeporn Ruangchuay, Anong Chirapart   +6 more
doaj   +1 more source

TYROSINASE AND PLANT RESPIRATION [PDF]

Journal of General Physiology, 1943
The evidence presented in this paper supports the conclusion that at least 85 per cent of the oxygen uptake of the respiring tissue of potato tuber enters the chemistry of the cell by way of a tyrosinase-catalyzed oxidation. The qualitative aspects of this conclusion are in agreement with the claim made by Boswell and Whiting.
D, Baker, J M, Nelson
openaire   +2 more sources

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Histidine residues at the copper-binding site in human tyrosinase are essential for its catalytic activities

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Tyrosinase is a copper-binding enzyme involved in melanin biosynthesis. However, the detailed structure of human tyrosinase has not yet been solved, along with the identification of the key sites responsible for its catalytic activity.
Hyangsoon Noh, Sung Jun Lee, Hyun-Joo Jo, H. Choi, Sungguan Hong, K. Kong   +5 more
semanticscholar   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source