Results 21 to 30 of about 45,442 (272)

Phlorotannins Derived From the Brown Alga as Tyrosinase Inhibitors

Natural Product Communications, 2021
Tyrosinase catalyzes hydroxylation of L-tyrosine and dehydrogenation of L-DOPA in the melanin biosynthesis pathway. Tyrosinase inhibitors have potential use as cosmetic whitening agents and for preventing seafood deterioration. In this report, tyrosinase
Hideyuki Kurihara, Kazuki Kujira
doaj   +1 more source

Influence of the polyunsaturated fatty acids linoleic acid, arachidonic acid, [alpha]-linolenic acid and [gamma]-linolenic acid on melanogenesis of B16 mouse melanoma cells and normal human melanocytes [PDF]

, 2002
The influence of the polyunsaturated fatty acids (PUFA) linoleic acid, arachidonic acid, α-linolenic acid and γ-linolenic acid on pigmentation was examined using different in vitro models: monolayer cultures of B16 mouse melanoma cells, monolayer ...
Stöckli, Martin
core   +1 more source

A Potent Tyrosinase Inhibitor, (E)-3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one, with Anti-Melanogenesis Properties in α-MSH and IBMX-Induced B16F10 Melanoma Cells

Molecules, 2018
In this study, we designed and synthesized eight thiophene chalcone derivatives (1a–h) as tyrosinase inhibitors and evaluated their mushroom tyrosinase inhibitory activities.
Chang Seok Kim, Sang Gyun Noh, Yujin Park, Dongwan Kang, Pusoon Chun, Hae Young Chung, Hee Jin Jung, Hyung Ryong Moon   +7 more
doaj   +1 more source

Inhibitory Effects of Urginea maritima (L.) Baker, Zhumeria majdae Rech. F. and Wendelbo and Physalis divaricata D. Don Ethanolic Extracts on Mushroom Tyrosinase

Pharmaceutical Sciences, 2016
Background: Tyrosinase is a key enzyme in melanin synthesis from tyrosine. To prevent or treat pigmentation disorders, tyrosinase inhibitors have been used increasingly for medicinal and cosmetic products.
Foroogh Namjoyan, Alireza Jahangiri, Mohammad Ebrahim Azemi, Hamideh Mousavi
doaj   +1 more source

A Novel Class of Potent Anti-Tyrosinase Compounds with Antioxidant Activity, 2-(Substituted phenyl)-5-(trifluoromethyl)benzo[d]thiazoles: In Vitro and In Silico Insights

Antioxidants, 2022
Sixteen compounds bearing a benzothiazole moiety were synthesized as potential tyrosinase inhibitors and evaluated for mushroom tyrosinase inhibitory activity.
YeJi Hwang, Jieun Lee, Hee Jin Jung, Sultan Ullah, Jeongin Ko, Yeongmu Jeong, Yu Jung Park, Min Kyung Kang, Hwayoung Yun, Min-Soo Kim, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon   +12 more
doaj   +1 more source

Data in support of covalent attachment of tyrosinase onto cyanuric chloride crosslinked magnetic nanoparticles

Data in Brief, 2016
Preparation and characterization of cross linked amine-functionalized magnetic nanoparticles as an appropriate support for covalent immobilization on tyrosinase was presented in the study "Covalent immobilization of tyrosinase onto cyanuric chloride ...
Kourosh Abdollahi, Farshad Yazdani, Reza Panahi   +2 more
doaj   +1 more source

Copper–oxygen Dynamics in Tyrosinase [PDF]

, 2019
To unveil the activation of dioxygen on the copper centre (Cu2O2core) of tyrosinase, we performed X-ray crystallograpy with active-form tyrosinase at near atomic resolution.
Shinobu, Itoh, Nobutaka, Fujieda, Minoru, Kubo, Genji, Kurisu, Sachiko, Yanagisawa   +4 more
core   +2 more sources

Visualization of Intracellular Tyrosinase Activity in vitro

Bio-Protocol, 2016
Melanocytes produce the melanin pigments in melanosomes and these organelles protect the skin against harmful ultraviolet rays. Tyrosinase is the key cuproenzyme which initiates the pigment synthesis using its substrate amino acid tyrosine or L-DOPA (L-3,
Riddhi Jani, Sudeshna Nag, Subba Setty
doaj   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Screening of Peruvian Medicinal Plants for Tyrosinase Inhibitory Properties: Identification of Tyrosinase Inhibitors in Hypericum laricifolium Juss

Molecules, 2017
Tyrosinase inhibitors are of far-ranging importance in cosmetics, medicinal products, and food industries. Peru is a diverse country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. In the present study, the tyrosinase
Yanymee Nimesia Guillen Quispe, Seung Hwan Hwang, Zhiqiang Wang, Soon Sung Lim   +3 more
doaj   +1 more source