Synthesis, anti-browning effect and mechanism research of kojic acid-coumarin derivatives as anti-tyrosinase inhibitors. [PDF]
He M +6 more
europepmc +1 more source
An Updated Review of Tyrosinase Inhibitors
Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing.
Te-Sheng Chang
exaly +2 more sources
Natural Melanogenesis Inhibitors Acting Through the Down-Regulation of Tyrosinase Activity
Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in melanogenesis, and the down-regulation of enzyme activity is the most reported ...
Te-Sheng Chang
exaly +2 more sources
New halogenated phenylcoumarins as tyrosinase inhibitors
With the aim to find out structural features for the tyrosinase inhibitory activity, in the present communication we report the synthesis and pharmacological evaluation of a new series of phenylcoumarin derivatives with different number of hydroxyl or ...
Lourdes Santana +2 more
exaly +2 more sources
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