Results 31 to 40 of about 674,878 (317)

Novel Strecker degradation products of tyrosine and dihydroxyphenylalanine

Czech Journal of Food Sciences, 2001
Tyrosine was oxidised with either potassium peroxodisulphate or glyoxal. Volatile reaction products were isolated and analysed by GC/FID and GC/MS, derivatised with diazomethane and analysed by the same methods.
J. Adamiec, K. Cejpek, J. Rössner, J. Velíšek   +3 more
doaj   +1 more source

Effects of Dietary Phenylalanine and Tyrosine Supplements on the Chronic Stress Response in the Seabream (Sparus aurata)

Frontiers in Physiology, 2022
The increase of aquaculture production is associated with a growing interest in improving physiological status and welfare in fish. For this reason, the search for strategies for mitigating stress has been intensified, with one of these strategies being ...
Natalia Salamanca, Oscar Moreno, Inmaculada Giráldez, Emilio Morales, Ignacio de la Rosa, Marcelino Herrera, Marcelino Herrera   +6 more
doaj   +1 more source

Method development and validation for analysis of phenylalanine, 4‐hydroxyphenyllactic acid and 4‐hydroxyphenylpyruvic acid in serum and urine

JIMD Reports, 2022
Alkaptonuria (AKU) is a rare debilitating autosomal recessive disorder of tyrosine (TYR) metabolism which results in a deficiency of the enzyme homogentisate 1,2‐dioxygenase activity.
Andrew T. Hughes, Anna M. Milan, Ella Shweihdi, James Gallagher, Lakshminarayan Ranganath   +4 more
doaj   +1 more source

On the Applicability of Chitosan Oligomers-Amino Acid Conjugate Complexes as Eco-Friendly Fungicides against Grapevine Trunk Pathogens

Agronomy, 2021
In a context in which the incidence and severity of grapevine fungal diseases is increasing as a result of both climate change and modern management culture practices, reducing the excessive use of phytosanitary products in viticulture represents a major
Laura Buzón-Durán, Natalia Langa-Lomba, Vicente González-García, José Casanova-Gascón, Jesús Martín-Gil, Eduardo Pérez-Lebeña, Pablo Martín-Ramos   +6 more
doaj   +1 more source

High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

Frontiers in Public Health, 2023
BackgroundPrevious research has outlined the health benefits of exercise including its therapeutic potential for substance use disorders (SUD). These data have already been utilized and it is now common to find exercise as part of SUD treatment and ...
John Tyler, John Tyler, Madeline Podaras, Madeline Podaras, Brittany Richardson, Brittany Richardson, Nicole Roeder, Nicole Roeder, Nikki Hammond, John Hamilton, Kenneth Blum, Mark Gold, David A. Baron, Panayotis K. Thanos, Panayotis K. Thanos   +14 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Exploring the Interaction of Indole-3-Acetonitrile with Neuroblastoma Cells: Understanding the Connection with the Serotonin and Dopamine Pathways

Biomedicines, 2023
Indole-3-acetonitrile, a compound produced by bacteria and plants as a defense and survival signal in response to attacks, has been recently discovered as a metabolite produced by human cancer cells.
Catarina Moura, Ana Salomé Correia, Nuno Vale   +2 more
doaj   +1 more source

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 [PDF]

Journal of Clinical Investigation, 2016
Inflammasomes form as the result of the intracellular presence of danger-associated molecular patterns and mediate the release of active IL-1β, which influences a variety of inflammatory responses. Excessive inflammasome activation results in severe inflammatory conditions, but physiological IL-1β secretion is necessary for intestinal homeostasis. Here,
Spalinger Marianne, Kasper Stephanie, Gottier Claudia, Lang Silvia, Atrott Kirstin, Vavricka Stephan, Scharl Sylvie, Gutte Peter, Grütter Markus, Beer Hans-Dietmar, Contassot Emmanuel, Chan Andrew, Dai X, Rawlings David, Mair Florian, Becher Burkhard, Frey Isabelle, Raselli Tina, Falk Werner, Fried Michael, Rogler Gerhard, Scharl Michael   +21 more
openaire   +7 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Screening and Structure–Activity Relationship for Selective and Potent Anti-Melanogenesis Agents Derived from Species of Mulberry (Genus Morus)

Molecules, 2022
Tyrosinase is a multifunctional, copper-containing and rate-limiting oxidase that catalyses crucial steps in the melanogenesis pathway and is responsible for skin-pigmentation abnormalities in mammals.
Anna Gryn-Rynko, Beata Sperkowska, Michał S. Majewski   +2 more
doaj   +1 more source