Results 31 to 40 of about 1,001,494 (307)

Effects of Dietary Phenylalanine and Tyrosine Supplements on the Chronic Stress Response in the Seabream (Sparus aurata)

Frontiers in Physiology, 2022
The increase of aquaculture production is associated with a growing interest in improving physiological status and welfare in fish. For this reason, the search for strategies for mitigating stress has been intensified, with one of these strategies being ...
Natalia Salamanca, Oscar Moreno, Inmaculada Giráldez, Emilio Morales, Ignacio de la Rosa, Marcelino Herrera, Marcelino Herrera   +6 more
doaj   +1 more source

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Journal of Biological Chemistry, 1987
Tyrosine-specific protein kinase activity of the epidermal growth factor (EGF) receptor, pp60v-src and pp110gag-fes was inhibited in vitro by an isoflavone genistein.
Tetsu AkiyamaSO, Junko IshidaST, Suguru NakagawaS, H. Ogawara, Shun‐ichi Watanabe, Noriki Itoh, Masabumi ShibuyaSS, Y. Fukami   +7 more
semanticscholar   +1 more source

Increased prevalence of Parkinson's disease in alkaptonuria

JIMD Reports, 2023
Amongst a cohort of 88 alkaptonuria (AKU) patients attending the United Kingdom National Alkaptonuria Centre (NAC), four unrelated patients had co‐existing Parkinson's disease (PD).
Lakshminarayan Ranganath, Milad Khedr, Anna M. Milan, Andrew S. Davison, Brendan P. Norman, Mirian C. H. Janssen, Edward Lock, George Bou‐Gharios, James A. Gallagher   +8 more
doaj   +1 more source

L-DOPA Trends in Different Tissues at Early Stages of Vicia faba Growth: Effect of Tyrosine Treatment

Applied Sciences, 2018
The nonprotein amino acid Levo-3,4-dihydroxyphenylalanine (L-DOPA) has insecticidal, allelochemical, and antiparkinsonian effects. The aim of this research was to assess L-DOPA content in different tissues of Vicia faba (cv.
Claudia A. Oviedo-Silva, Mhartyn Elso-Freudenberg, Mario Aranda-Bustos   +2 more
doaj   +1 more source

Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

Nature Communications, 2019
Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study, we characterize gut-associated bacteria in their ability to decarboxylate levodopa to dopamine
S. V. van Kessel, Alexandra K. Frye, A. El-Gendy, M. Castejon, A. Keshavarzian, G. van Dijk, Sahar El Aidy   +6 more
semanticscholar   +1 more source

Mechanisms of receptor tyrosine kinase activation in cancer

Molecular Cancer, 2018
Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes including growth, motility, differentiation, and metabolism.
Z. Du, C. Lovly
semanticscholar   +1 more source

Performance of piglets in response to the standardized ileal digestible phenylalanine and tyrosine supply in low-protein diets

Animal, 2014
Reducing the CP level of the diet allows for a reduction in N excretion without limiting performance as long as the amino acid (AA) requirements are covered. The availability of crystalline AA has permitted for a considerable reduction in the CP level of
M. Gloaguen, N. Le Floc’h, Y. Primot, E. Corrent, J. van Milgen   +4 more
doaj   +1 more source

Effect of large neutral amino acids treatment on blood phenylalanine, tyrosine, and tryptophan levels in adolescent and young adult PKU patients

Trends in Pediatrics
Objective: We aimed to evaluate the change in phenylalanine (Phe), Tyrosine (Tyr), and Tryptophan (Trp) blood levels in classical PKU patients treated with large neutral amino acids (LNAA) supplementation.
Fehime Erdem, Ebru Canda, Havva Yazıcı, Yasemin Atik Altınok, Merve Yoldaş Çelik, Ayşe Yüksel Yanbolu, Sema Kalkan Uçar, Sara Habif, Mahmut Çoker   +8 more
doaj   +1 more source

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Journal of Biological Chemistry, 1996
Here, we have studied the activity of a novel protein-tyrosine kinase inhibitor that is selective for the Src family of tyrosine kinases. We have focused our study on the effects of this compound on T cell receptor-induced T cell activation, a process ...
J. Hanke, J. Gardner, R. L. Dow, P. Changelian, W. Brissette, E. J. Weringer, B. Pollok, P. Connelly   +7 more
semanticscholar   +1 more source

Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors

Pteridines, 2015
Formation of neopterin, a biomarker of the activated human immune system, is linked with tryptophan (TRP) and phenylalanine (PHE) metabolism. To obtain normal values, in this study, serum concentrations of neopterin as well as of TRP, PHE and their ...
Geisler Simon, Mayersbach Peter, Becker Kathrin, Schennach Harald, Fuchs Dietmar, Gostner Johanna M.   +5 more
doaj   +1 more source