Results 111 to 120 of about 207,078 (211)

Reactive Nitrogen Species and Fibrinogen: Exploring the Effects of Nitration on Blood Clots

Antioxidants
Reactive nitrogen species (RNS), particularly peroxynitrite (ONOO−), play a central role in post-translational modifications (PTMs) of proteins, including fibrinogen, a key component of the coagulation cascade.
Francesca Nencini, Serena Borghi, Elvira Giurranna, Ilenia Barbaro, Niccolò Taddei, Claudia Fiorillo, Matteo Becatti   +6 more
doaj   +1 more source

Insights Into the Mechanism of Tyrosine Nitration in Preventing β-Amyloid Aggregation in Alzheimer's Disease. [PDF]

Front Mol Neurosci, 2021
Zhao J, Shi Q, Zheng Y, Liu Q, He Z, Gao Z, Liu Q.   +6 more
europepmc   +1 more source

Curcumin Intervention in Diabetic Neuropathy: Molecular Mechanisms and Preclinical Insights

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review highlights curcumin's neuroprotective potential, showing how it mitigates oxidative stress and inflammation by modulating Nrf2, MAPK, and NF‐κB signaling. Preclinical data shows it stabilizes glucose metabolism and reduces nerve degradation.
Sanket Sharma, Rosaline Mishra, Rashmi Singh, Radha Goel, Praveen Kumar Gaur, Kanak Lata   +5 more
wiley   +1 more source

Amino Acid Modified Polymer Mesh for Removal of the Heavy Metal Ions Pb2+, Hg2+, Cu2+, and Ni2+ From Aqueous Solutions

Chemie Ingenieur Technik, Volume 98, Issue 11, Page 702-712, November 2026.
Adsorbents for cations of copper, lead, mercury, and nickel are obtained via grafting polymer mesh with an acrylic acid copolymer and subsequent functionalization with an amino acid. A distinct influence of the type of amino acid on the adsorption occurs.
Claudia Adolfs, Jan Becker, Hoang‐My Pham‐Cong, Uwe Gohs, Axel Fischer, Marco Drache, Sabine Beuermann   +6 more
wiley   +1 more source

pH Profile of cytochrome c-catalyzed tyrosine nitration [PDF]

, 2006
In the present study, we investigated how cytochrome c catalyzed the nitration of tyrosine at various pHs. The cytochrome c-catalyzed nitration of tyrosine occurred in proportion to the concentration of hydrogen peroxide, nitrite or cytochrome c ...
Okuda, Junna, Takigawa, Tomoko, Kambayashi, Yasuhiro, Shibamori, Masafumi, Ogino, Keiki, Hitomi, Yoshiaki, Kodama, Norio, Takemoto, Kei, Kubo, Masayuki   +8 more
core  

YY1 nitration participates in DbCM cardiomyocyte lipotoxicity by inhibiting ANXA3-induced microlipophagy

Redox Biology
Aims: Diabetic cardiomyopathy (DbCM), a severe complication of type 2 diabetes mellitus (T2DM), is pathologically characterized by myocardial lipid deposition leading to cardiomyocyte lipotoxic injury.
Jiayin Chai, Lijie Han, Degang Mo, Yunfei Bai, Yiming Yang, Yuqing Ding, Shuai Chen, Xiangning Kong, Xinyu Zhu, Lijia Xu, Hongyan Dai, Wen Wang   +11 more
doaj   +1 more source

Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin Breakdown and Protein Tyrosine Nitration

Journal of Pharmacological Sciences, 2005
We here assessed the effects of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, on infarct size in the rat heart subjected to ...
Masami Hashimoto, Yoko Takada, Yusuke Takeuchi, Jiro Kasahara, Hiroaki Hisa, Yasufumi Shirasaki, Kohji Fukunaga   +6 more
doaj   +1 more source

Tyrosine Nitration on p65 [PDF]

Molecular & Cellular Proteomics, 2005
Sung Wook Park, M.D.Mostaqul Huq, Xinli Hu, Li-Na Wei   +3 more
openaire   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi, Morteza Fallahpour, Mohammad Nabavi, Maryam Jalessi, Hadi Ghanbari, Nasibeh Khayer, Farzad Taghizadeh‐Hesary   +6 more
wiley   +1 more source