Results 251 to 260 of about 1,485,018 (348)

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source

Influence of BMI, Cigarette Smoking and Cryopreservation on Tyrosine Phosphorylation during Sperm Capacitation. [PDF]

Int J Mol Sci
Ortiz-Vallecillo A, Santamaría-López E, García-Ruiz D, Martín-Lozano D, Candenas L, Pinto FM, Fernández-Sánchez M, González-Ravina C.   +7 more
europepmc   +1 more source

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation.

Proceedings of the National Academy of Sciences of the United States of America, 2000
M. Stein, R. Rappuoli, A. Covacci
semanticscholar   +1 more source

A review of the inhibitory waste metabolites produced during mAb biomanufacturing

Biotechnology Progress, EarlyView.
The review highlights inhibitory metabolites in CHO cell cultures, such as lactate, ammonia, isobutyrate, and isovalerate, impacting growth and productivity. Identification methods include LC/MS‐based metabolomics, while control strategies involve media optimization, genetic engineering, and process adjustments (pH, temperature).
Zhao Wang, Caitlin Morris, Duc Hoang, Jianlin Xu, Michael C. Borys, Seongkyu Yoon   +5 more
wiley   +1 more source

Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis. [PDF]

J Neuroinflammation
Yang S, Du Y, Li Y, Tang Q, Zhang Y, Zhao X.   +5 more
europepmc   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Protein palmitoylation is involved in regulating mouse sperm motility via the signals of calcium, protein tyrosine phosphorylation and reactive oxygen species. [PDF]

Biol Res
Xiong Y, Yi C, Zheng H, Ni Y, Xue Y, Li K.   +5 more
europepmc   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Activating pyruvate kinase improves red blood cell integrity by reducing band 3 tyrosine phosphorylation. [PDF]

Blood Adv
Le K, Wang X, Chu J, Lundt M, Lee YY, Conrey A, Frey I, Giannini S, Kosinski PA, Hausman JM, Low PS, Jeffries N, Desai SA, Thein SL.   +13 more
europepmc   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source