Results 51 to 60 of about 205,532 (202)
Towards a more accurate annotation of tyrosine-based site-specific recombinases in bacterial genomes [PDF]
Mobile DNA, 2012 Abstract Background Tyrosine-based site-specific recombinases (TBSSRs) are DNA breaking-rejoining enzymes. In bacterial genomes, they play a major role in the comings and goings of mobile genetic elements (MGEs), such as temperate phage genomes, integrated conjugative elements (ICEs) or integron cassettes.
Van Houdt, Rob +4 more
openaire +4 more sources
Integrase-associated niche differentiation of endogenous large DNA viruses in crustaceans
Microbiology SpectrumCrustacean genomes harbor sequences originating from nimaviruses, a family of large double-stranded DNA viruses infecting crustaceans. In this study, we recovered metagenome-assembled genomes of 27 endogenous nimaviruses from crustacean genome data ...
Satoshi Kawato +3 more
doaj +1 more source
, 2020 Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020) +5 more
core +1 more source
Frontiers in Molecular Neuroscience, 2020 Techniques that allow the manipulation of specific neural circuits have greatly increased in the past few years. DREADDs (Designer receptors exclusively activated by designer drugs) provide an elegant way to manipulate individual brain structures and/or ...
Juan-Carlos Cerpa +10 more
doaj +1 more source
Helicobacter Pylori's plasticity zones are novel transposable elements. [PDF]
PLoS ONE, 2009 BACKGROUND:Genes present in only certain strains of a bacterial species can strongly affect cellular phenotypes and evolutionary potentials. One segment that seemed particularly rich in strain-specific genes was found by comparing the first two sequenced
Dangeruta Kersulyte +10 more
doaj +1 more source
, 2020 Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020) +5 more
core +1 more source
Nucleic Acids Research, 2023 Abstract Tyrosine-type site-specific recombinases (Y-SSRs) are versatile tools for genome engineering due to their ability to mediate excision, integration, inversion and exchange of genomic DNA with single nucleotide precision. The ever-increasing need for sophisticated genome engineering is driving efforts to identify novel SSR systems
Milica Jelicic +7 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 2020 Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020) +5 more
core +1 more source
The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis
Asian Journal of Andrology, 2020 The transition from spermatogonia to spermatocytes and the initiation of meiosis are key steps in spermatogenesis and are precisely regulated by a plethora of proteins. However, the underlying molecular mechanism remains largely unknown.
Yang Li +11 more
doaj +1 more source