Results 41 to 50 of about 205,532 (202)

Characterization of the integration and modular excision of the integrative conjugative element PAISt in Streptomyces turgidiscabies Car8. [PDF]

open access: yesPLoS ONE, 2014
PAISt is a large genomic island located in the chromosome of the plant pathogen Streptomyces turgidiscabies Car8. The island carries clustered virulence genes, transfers to other Streptomyces species, and integrates by site-specific recombination at the ...
Jose C Huguet-Tapia   +2 more
doaj   +1 more source

Protein tyrosine phosphatase TbPTP1:A molecular switch controlling life cycle differentiation in trypanosomes [PDF]

open access: yes, 2006
Differentiation in African trypanosomes (Trypanosoma brucei) entails passage between a mammalian host, where parasites exist as a proliferative slender form or a G0-arrested stumpy form, and the tsetse fly.
Szoor, Balazs; id_orcid   +12 more
core   +1 more source

The unconventional Xer recombination machinery of Streptococci/Lactococci.

open access: yesPLoS Genetics, 2007
Homologous recombination between circular sister chromosomes during DNA replication in bacteria can generate chromosome dimers that must be resolved into monomers prior to cell division.
Pascal Le Bourgeois   +8 more
doaj   +1 more source

Nearest-neighbor amino acids of specificity-determining residues influence the activity of engineered Cre-type recombinases

open access: yesScientific Reports, 2020
The tyrosine-type site-specific DNA recombinase Cre recombines its target site, loxP, with high activity and specificity without cross-recombining the target sites of highly related recombinases. Understanding how Cre achieves this precision is key to be
Anjali Soni   +3 more
doaj   +1 more source

Dissecting the roles of XerC and XerD in Xer site-specific recombination [PDF]

open access: yes, 2002
The tyrosine recombinases XerC and XerD function in the monomerisation of circular dimer replicons in many bacteria. The recombining complex contains two synapsed recombination sites and two molecules each of XerC and XerD. Recombination proceeds through
Ferreira, Henrique, Ferreira, Henrique.
core   +1 more source

The IntI-Like Tyrosine Recombinase ofShewanella oneidensisIs Active as an Integron Integrase [PDF]

open access: yesJournal of Bacteriology, 2002
ABSTRACTWe have found an integron-like integrase gene and anattIsite inShewanella oneidensisas part of a small chromosomal integron. We have cloned this gene and tested the ability of the integrase to excise cassettes from various integrons. Most cassettes flanked by twoattCsites are readily excised, while cassettes in the “first” position, with ...
François, Drouin   +2 more
openaire   +2 more sources

Initial characterization of the Pf-Int recombinase from the malaria parasite Plasmodium falciparum.

open access: yesPLoS ONE, 2012
BackgroundGenetic variation is an essential means of evolution and adaptation in many organisms in response to environmental change. Certain DNA alterations can be carried out by site-specific recombinases (SSRs) that fall into two families: the serine ...
Mehdi Ghorbal   +9 more
doaj   +1 more source

pGIAK1, a heavy metal resistant plasmid from an obligate alkaliphilic and halotolerant bacterium isolated from the Antarctic Concordia station confined environment. [PDF]

open access: yesPLoS ONE, 2013
pGIAK1 is a 38-kb plasmid originating from the obligate alkaliphilic and halotolerant Bacillaceae strain JMAK1. The strain was originally isolated from the confined environments of the Antarctic Concordia station.
Suxia Guo, Jacques Mahillon
doaj   +1 more source

Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

open access: yeseLife, 2020
Engineered allosteric regulation of protein activity provides significant advantages for the development of robust and broadly applicable tools. However, the application of allosteric switches in optogenetics has been scarce and suffers from critical ...
Mark Shaaya   +14 more
doaj   +1 more source

Tyrosine recombinase phylogeny.

open access: yes, 2016
Maximum likelihood phylogenetic tree of tyrosine recombinase gene (xis) nucleotide sequences and data characterizing the element each xis gene is found on. Shaded boxes group element variants together.
John C. Meeks (2521087)   +2 more
core   +1 more source

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