Results 121 to 130 of about 4,897 (216)

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Tangle analysis of DNA unlinking by the Xer/FtsK system(Knots and soft-matter physics: Topology of polymers and related topics in physics, mathematics and biology) [PDF]

, 2009
この論文は国立情報学研究所の電子図書館事業により電子化されました。DNAに作用する部位特異的組み換え酵素の働きは、タングルを用いてモデル化され、得られるタングル方程式を数学の結果を用いて解くことにより、部位特異的酵素の働きのトポロジーの特徴付けが出来る。ここでは、Grainge等(2007)によって示された部位特異的Xer/FtsKシステムによるDNA絡み目解消操作の解析を行い、その特徴付けを述べる。特にその作用を特徴付ける主要なタングルが有理タングルとなることを示す。The action of ...
Ishihara, Kai, Shimokawa, Koya, Vazquez, Mariel   +2 more
core  

Principles of genetic circuit design [PDF]

, 2014
Cells navigate environments, communicate and build complex patterns by initiating gene expression in response to specific signals. Engineers seek to harness this capability to program cells to perform tasks or create chemicals and materials that match ...
A Espah Borujeni, A Garg, A Prindle, A Tamsir, A Villalobos, AA Nielsen, AE Friedland, AH Becker, AI Yao, AP Arkin, AP Arkin, AS Khalil, B Calles, B Canton, B Paetzold, B Wang, B-K Cho, BC Stanton, C Engler, C Lou, C Lou, C Ma, CA Voigt, CA Voigt, CC Guet, CC Liu, CC Liu, CH Collins, Christopher A Voigt, D Bikard, D Chen, D Del Vecchio, D Endy, DB Goodman, DE Koshland, DG Gibson, DG Sashital, DK Karig, DL Shis, DM Widmaier, DM Widmaier, DN Gopaul, E Deltcheva, E Fung, E Karzbrun, E Levine, EA Davidson, EA Lesnik, EJ Archer, EL Haseltine, F Aquea, F Ceroni, F Farzadfard, F Lienert, F Moser, F Yaman, F Zhang, F Zhang, FK Balagaddé, G Cambray, G Kudla, G Rodrigo, G Schendzielorz, GA Khoury, H Dong, H Niederholtmeyer, H Nishimasu, H Tagami, H-J Frasch, HM Salis, IL Grigorova, J Ang, J Bonnet, J Bonnet, J Hasty, J Hasty, J Shen, J Shin, J Shong, J Stricker, J Zhan, J-H Seo, J-P Motta, JA Dietrich, JA Stapleton, JC Anderson, JC Anderson, JC Liang, JD Kittle, Jennifer A N Brophy, JH Davis, JH Huh, JH Levine, JJ Lohmueller, JJ Tabor, JM Callura, JM Vilar, JR Kelly, JT Kittleson, JW Ellefson, K Bernhardt, K Clancy, K Krishnanathan, K Temme, K Temme, K Volzing, K Weller, KA Walker, KI Ramalingam, KM Esvelt, KM Esvelt, L Bintu, L Bintu, L Huynh, L Qi, L Qi, L Steidler, LA Gilbert, LS Qi, LWM Loo, M Fischbach, M Gossen, M Hucka, M Leguia, M Ptashne, M Scott, M Tigges, MB Elowitz, MH Larson, MH Medema, MJ Moscou, MJL de Hoon, ML Maeder, MR Atkinson, MS Antunes, MS Antunes, MS Lu, N Anesiadis, N Naryshkin, N Roehner, NA Cookson, NE Buchler, NE Buchler, NE Lewis, NJ Hillson, NT Ingolia, O Purcell, O Rackham, P Argos, P Bernard, P Mali, P Perez-Pinera, P Siuti, PD Hsu, PEM Purnick, PK Geyer, PP Peralta-Yahya, R Daniel, R Gaber, R Hussein, R Lentini, R Sorek, RC Brewster, RH Dahl, RR Beerli, RS Cox III., RW Simons, RWS Peacock, S Ausländer, S Basu, S Bhatia, S Cardinale, S Cardinale, S Chen, S de Kok, S Gottesman, S Gottesman, S Gupta, S Hooshangi, S Jayanthi, S Johnson, S Kosuri, S Legewie, S Regot, S Siedler, S Wang, SB Jonnalagadda, SC Sleight, SC Sleight, SC Sleight, SH Sternberg, ST Lovett, SW Seo, T Danino, T Umeyama, T-H Lee, T-M Yi, TS Gardner, TS Ham, TS Ham, TS Moon, TS Moon, V Noireaux, VA Rhodius, VA Rhodius, VK Mutalik, VK Mutalik, W Jeong, W Liu, W Weber, WA Lim, WC Ruder, WH Mather, WJ Holtz, X-X Xia, Y Takeda, Y Yokobayashi, Y-J Chen, Z Shao   +218 more
core   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

Homologous Recombination: To Fork and Beyond [PDF]

, 2018
Accurate completion of genome duplication is threatened by multiple factors that hamper the advance and stability of the replication forks. Cells need to tolerate many of these blocking lesions to timely complete DNA replication, postponing their repair ...
Prado Velasco, José Félix
core   +1 more source

A NaV1.8FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

Frontiers in Molecular Neuroscience
Genetic targeting of select populations of cells in the mouse nervous system is often hampered by a lack of selectivity, as candidate genes for such targeting are commonly expressed by multiple cell populations, also in the same region.
John C. Y. Chen, Lech Kaczmarczyk, Lech Kaczmarczyk, Walker S. Jackson, Walker S. Jackson, Max Larsson   +5 more
doaj   +1 more source

Binary recombinase systems for high-resolution conditional mutagenesis [PDF]

, 2017
Conditional mutagenesis using Cre recombinase expressed from tissue specific promoters facilitates analyses of gene function and cell lineage tracing. Here, we describe two novel dual-promoter-driven conditional mutagenesis systems designed for greater ...
Hermann, Mario, Kapp, Viktor, Mercader, Nadia, Montoliu, Lluís, Pelczar, Pawel, Seruggia, Davide, Stillhard, Patrick, Sánchez-Iranzo, Héctor, Wildner, Hendrik, Zeilhofer, Hanns Ulrich   +9 more
core  

Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]

, 2013
Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Best, AA, Broussard, GW, Connerly, PL, Conway, JF, Dedrick, RM, Hatfull, GF, Hendrix, RW, Jacobs-Sera, D, Kremer, TA, Offner, S, Ogiefo, AH, Pizzorno, MC, Pope, WH, Rockenbach, K, Russell, DA, Stowe, EL, Stukey, J, Thibault, SA   +17 more
core   +4 more sources

Differential recognition of the Multiple Banded Antigen isoforms across Ureaplasma parvum and Ureaplasma urealyticum species by monoclonal antibodies [PDF]

, 2016
Two separate species of Ureaplasma have been identified that infect humans: Ureaplasma parvum and Ureaplasma urealyticum. Most notably, these bacteria lack a cell wall and are the leading infectious organism associated with infection-related induction of
Aboklaish, Ali, Ahmed, S., Cassell, G., McAllister, D., Spiller, Owen Bradley, Zheng, X.   +5 more
core   +2 more sources

The Tn916/Tn1545 Family of Conjugative Transposon [PDF]

, 2013
The conjugative transposon Tn916 was first discovered in the late 1970s and is, together with the related conjugative transposon Tn1545, the paradigm of a large family of related conjugative transposons known as the Tn916/Tn1545 family, which are found ...
Agerso, Y, Ciric, L, de Vries, EL, Jasni, A, Mullany, P, Roberts, AP   +5 more
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