Quantifying Deformation and Migration Properties of U87 Glioma Cells Using Dielectrophoretic Forces [PDF]
Biosensors, 2022 Glioblastoma multiforme is one of the most aggressive malignant primary brain tumors. To design effective treatment strategies, we need to better understand the behavior of glioma cells while maintaining their genetic and phenotypic stability.
Meltem Elitas +6 more
doaj +6 more sources
Single-Cell Mechanophenotyping in Microfluidics to Evaluate Behavior of U87 Glioma Cells [PDF]
Micromachines, 2020 Integration of microfabricated, single-cell resolution and traditional, population-level biological assays will be the future of modern techniques in biology that will enroll in the evolution of biology into a precision scientific discipline.
Esra Sengul, Meltem Elitas
doaj +7 more sources
Exosomal miRNA-21 from Toxoplasma gondii-infected microglial cells induces the growth of U87 glioma cells by inhibiting tumor suppressor genes [PDF]
Scientific Reports, 2022 Toxoplasma gondii is an intracellular protozoan parasite that can modulate the microenvironment of infected hosts and is known to be associated with the incidence of brain tumor growth.
Bong-Kwang Jung +3 more
doaj +2 more sources
GLUTAMINE DEPRIVATION AFFECTS THE EXPRESSION OF GENES WHICH CONTROL PYRUVATE DEHYDROGENASE ACTIVITY: THE IMPACT OF ERN1 KNOCKDOWN [PDF]
Biotechnologia Acta, 2022 The aim of the current investigation was to study the expression of genes encoded pyruvate dehydrogenase subunits (PDHA1, PDHB, PDHX, DLAT, and DLD) in U87 glioma cells in response to glutamine deprivation in U87 glioma cells in relation to knockdown of ...
M. Sliusar +3 more
doaj +1 more source
Shikonin kills glioma cells through necroptosis mediated by RIP-1. [PDF]
PLoS ONE, 2013 BACKGROUND AND PURPOSE: Shikonin was reported to induce necroptosis in leukemia cells, but apoptosis in glioma cell lines. Thus, it is needed to clarify whether shikonin could cause necroptosis in glioma cells and investigate its underlying mechanisms ...
Chuanjiang Huang +6 more
doaj +1 more source
GLUTAMINE DEPRIVATION EFFECT ON DEK, TPD52, BRCA1, ADGRE5, LIF, GNPDA1, AND COL6A1 GENE EXPRESSIONS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2017 To study effect of glutamine deprivation on the expression of genes encoding the key proliferation associated factors on a relation to inhibition of inositol requiring enzyme-1 IRE1 in U87 glioma cells was the aim of the research.
A. P. Kharkova +6 more
doaj +1 more source
陆军军医大学学报, 2023 Objective To investigate the role of silent information regulator 3 (Sirt3) in glioma U87 cells, and provide new targets for early diagnosis and treatment of glioma.
ZHANG Xudong +3 more
doaj +1 more source
Assessment of the proliferation status of glioblastoma cell and tumour tissue after nanoplatinum treatment. [PDF]
PLoS ONE, 2017 Glioblastoma is one of the most frequent primary brain tumours of the central nervous system, with a poor survival time. With inefficient chemotherapy, it is urgent to develop new strategies for tumour therapy.
Marta Kutwin +6 more
doaj +1 more source
Sevoflurane Induces Ferroptosis of Glioma Cells Through Activating the ATF4-CHAC1 Pathway
Frontiers in Oncology, 2022 ObjectiveTo clarify the function and mechanisms of sevoflurane (Sev) on ferroptosis in glioma cells.MethodsDifferent concentrations of Sev were used to treat glioma cells U87 and U251.
Yingyi Xu +14 more
doaj +1 more source
Cancer Cell International, 2020 Background Growing studies have focused on the role of microRNA-21 (miR-21) in glioma, thus our objective was to discuss the effect of M2 bone marrow-derived macrophage (BMDM)-derived exosomes (BMDM-Exos) shuffle miR-21 on biological functions of glioma ...
Fan Yang +5 more
doaj +1 more source