Results 91 to 100 of about 6,573 (167)

Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

open access: yes, 2005
The conjugation of small ubiquitin-like modifiers SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
Ellis Jaffray   +17 more
core   +1 more source

UBC9 transiently interacts with PR-Set7 in cells.

open access: yes, 2013
(A) HEK 293 cell lysates expressing FLAG-PR-Set7 or FLAG-null were immunoprecipitated with an UBC9 antibody. Western analysis of the input (In) and bound (B) fractions were analyzed using FLAG or UBC9 antibodies. (B) HEK 293 cells co-transfected with the
Judd C. Rice (178101)   +3 more
core   +1 more source

Dynamic changes in sumoylation related proteins SUMO1, SENP1, and UBC9 during the peri implantation period in mice

open access: yesScientific Reports
The healthy progression and termination of pregnancy depend critically upon embryo development, acquisition of uterine receptivity, implantation, and decidualization during the peri-implantation period.
Ezgi Golal, Cemre Nur Balci, Nuray Acar
doaj   +1 more source

HCMV UL44 interacts with human Ubc9.

open access: yes, 2012
(A) GST-pulldown assays showing interaction of purified GST or GST-UL44 with in vitro-expressed, radiolabeled Ubc9 (right panels), HCMV UL54 (central panels, positive control), and influenza A virus PB1 (left panels, negative control).
Elisa Sinigalia (119085)   +11 more
core   +1 more source

p53 mediate UBC9 accumulation triggered by HPV16 E6/E7.

open access: yes, 2017
(A) Left: Representative WB of HKs transduced with the indicated recombinant retroviral vectors and analyzed by immunoblotting using anti- UBC9 antibody. Right: quantification of the protein bands intensities, standardized to GAPDH levels.
Claudia Miccolo (377902)   +14 more
core   +1 more source

SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation

open access: yesCell Death and Disease
p14ARF is a lysine-less tumor suppressor that enhances SUMOylation of its interactors. Although p14ARF is known to interact with the E2 SUMO conjugating enzyme UBC9, the link between ARF and SUMOylation is poorly understood and the potential impact of ...
Ahmed El Motiam   +17 more
doaj   +1 more source

Identification and validation of reference genes for RT-qPCR analysis in Iris domestica under Cd stress

open access: yesHeliyon
Iris domestica is a widely used ornamental garden and important medicinal plant. Our previous studies have shown that it exhibits significant uptake and translocation capacity under Cd stress compared to other Iris species.
Beibei Su   +9 more
doaj   +1 more source

Coactivation of SF-1-Mediated Transcription of Steroidogenic Enzymes by Ubc9 and PIAS1

open access: yes, 2011
Steroidogenic factor-1 (SF-1) is a nuclear orphan receptor, which is essential for adrenal development and regulation of steroidogenic enzyme expression.
Ken Nakagawa   +12 more
core   +1 more source

Late autophagic defects account for UBC9 accumulation in HPV16 E6/E7 HKs and cervical lesions.

open access: yes, 2017
(A) Left: Confocal microscopy images of empty or HPV16 E6/E7 transduced HKs treated with vehicle or bafilomycin for 24 hours, and immunostained with antibody against UBC9 (green) and LC3 (red). Nuclei were stained with DAPI (blue).
Claudia Miccolo (377902)   +14 more
core   +1 more source

Non-fused and Ubc9-fused TTR influences general SUMOylation.

open access: yes, 2016
Each of protein—non-fused TTR (TTR), TTR fused to the N-terminus of Ubc9 (TTR_Ubc9), and non-fused Ubc9 or EGFP (control)—was co-expressed with EGFP-labelled SUMO-1 (ES1) or SUMO-3 (ES3) in HEK293 cells.
Katarzyna Sołtys (2921856)   +6 more
core   +1 more source

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