Foxl2, Sumo-1 and Ubc9 are expressed in mouse ovary.
, 2013 A. Pias1, Ubc9 and Sumo-1 are expressed in 4 week mouse ovaries: 4-week old mouse ovaries were lysed and analysed by immunoblotting with anti- Pias1, Ubc9, and Sumo-1 specific antibodies. 50 ug of protein were loaded in each lane. B.
Loredana Marcia (366559) +7 more
core +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Ubc9 Regulates Mitosis and Cell Survival during Zebrafish Development
, 2006 Many proteins are modified by conjugation with Sumo, a gene-encoded, ubiquitin-related peptide, which is transferred to its target proteins via an enzymatic cascade.
Matthias Hammerschmidt +3 more
core +1 more source
Protein SUMOylation Is Required for Regulatory T Cell Expansion and Function
Cell Reports, 2016 Foxp3-expressing regulatory T (Treg) cells are essential for immune tolerance; however, the molecular mechanisms underlying Treg cell expansion and function are still not well understood.
Xiao Ding +7 more
doaj +1 more source
Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvae. [PDF]
PLoS Pathogens, 2010 To counter systemic risk of infection by parasitic wasps, Drosophila larvae activate humoral immunity in the fat body and mount a robust cellular response resulting in encapsulation of the wasp egg.
Indira Paddibhatla +4 more
doaj +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
MedComm, Volume 7, Issue 7, July 2026.Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
Identification of Sumoylation Inhibitors Targeting a Predicted Pocket in Ubc9
, 2016 Sumoylation is a post-translational modification that plays an important role in a wide range of cellular processes. Among the proteins involved in the sumoylation pathway, Ubc9 is the sole E2-conjugating enzyme required for sumoylation and plays a ...
Mikako Hirohama (827601) +4 more
core +1 more source
Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9 [PDF]
, 2009 The E1 helicase from BPV and HPV16 interacts with Ubc9 to facilitate viral genome replication. We report that HPV11 E1 also interacts with Ubc9 in vitro and in the yeast two-hybrid system.
Titolo, Steve +4 more
core +1 more source
Sumoylation of human argonaute 2 at lysine-402 regulates its stability. [PDF]
PLoS ONE, 2014 Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small RNA pathway in vivo are still largely elusive.
Umut Sahin +4 more
doaj +1 more source
Hyaluronan (HA) Receptors: Discovery, Function & Pathology
Proteoglycan Research, Volume 4, Issue 3, July 2026.ABSTRACT Hyaluronan (HA) is typically a long polymer of the repeating disaccharide, glucuronic acid‐β‐(1‐3)‐N‐acetylglucosamine polymerized by β(1‐4) bonds, with no obvious active site for biological activity. However, this dynamic polymer is vital for life in all metazoans and has a diverse array of functional characteristics due to the proteins that ...
Abby E. Bopp +8 more
wiley +1 more source