Results 101 to 110 of about 25,325 (230)

Prospects of Intravenous Coenzyme Q10 Administration in Emergency Ischemic Conditions

Life
Coenzyme CoQ10 (CoQ10) is an endogenous lipid-soluble antioxidant that effectively protects lipids, proteins, and DNA from oxidation due to its ability to undergo redox transitions between oxidized and reduced forms.
Elena I. Kalenikova, Evgeniya A. Gorodetskaya, Oxana V. Povarova, Oleg S. Medvedev   +3 more
doaj   +1 more source

Ubiquinone supplementation during lovastatin treatment: effect on LDL oxidation ex vivo1

Journal of Lipid Research, 1998
A randomized, double-masked, placebo-controlled cross-over trial was carried out to evaluate whether ubiquinone supplementation (180 mg daily) corrects impaired defence against initiation of oxidation of low density lipoprotein (LDL) related to effective
Ari Palomäki, Kimmo Malminiemi, Tiina Solakivi, Outi Malminiemi   +3 more
doaj   +1 more source

Fruit respiration: putting alternative pathways into perspective

New Phytologist, Volume 250, Issue 1, Page 54-73, April 2026.
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez, Sergio García‐Carbonell, Alisdair R. Fernie, Marta Pujol, Igor Florez‐Sarasa   +4 more
wiley   +1 more source

The Effects of Ubiquinol Intake and Sociophysical Training on the Activation of Psychological and Infrared Camera-Measured Body Temperature Physiology and Blood Molecular Markers: A Pilot Study among Healthy Female Older Adults

Applied Sciences
A combination of existing treatments with sensing technology may be the most appropriate approach for incurable neuropsychiatric disorders. Dietary antioxidant supplementation, exercise, and cognitive training are individually well-established treatments
Makoto Ota, Masanori Hariyama, Ricki Colman, Mamiko Koshiba   +3 more
doaj   +1 more source

Study protocol, randomized controlled trial: reducing symptom burden in patients with heart failure with preserved ejection fraction using ubiquinol and/or D-ribose

BMC Cardiovascular Disorders, 2018
Background Heart failure (HF), the leading cause of morbidity and mortality in the US, affects 6.6 million adults with an estimated additional 3 million people by 2030.
Janet D. Pierce, Diane E. Mahoney, John B. Hiebert, Amanda R. Thimmesch, Francisco J. Diaz, Carol Smith, Qiuhua Shen, Dinesh Pal Mudaranthakam, Richard L. Clancy   +8 more
doaj   +1 more source

Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing

The Journal of Physiology, Volume 604, Issue 7, Page 2898-2922, 1 April 2026.
Abstract figure legend Chronic oral supplementation with the mitochondria‐targeted antioxidant MitoQ (4 weeks; 250 µm) mitigates age‐related physical dysfunction in old mice, which is associated with reductions in skeletal muscle mitochondria‐specific superoxide and markers of mitochondrial reactive oxygen species (mitoROS)‐related oxidative stress and
Kevin O. Murray, Rachel A. Gioscia‐Ryan, Jaime N. Justice, Jessica R. Santos‐Parker, Nina Z. Bispham, David A. Hutton, Sanna Darvish, Jill Miyamoto‐Ditmon, Zachary S. Clayton, Michel Chonchol, Douglas R. Seals, Matthew J. Rossman   +11 more
wiley   +1 more source

Effects of Cannabidiol on TAFAZZIN‐Deficient B‐Lymphoblastoid Cells

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Deficiency of the cardiolipin remodeling enzyme TAFAZZIN causes Barth syndrome (BTHS), resulting in cardiolipin loss, monolysocardiolipin (MLCL) accumulation, and electron transport chain (ETC) abnormalities in B‐lymphoblastoid cells. Effects of the non‐psychotropic phytocannabinoid cannabidiol (CBD) were examined on B‐lymphoblastoid cells from ...
John Z. Chan, Antonia N. Berdeklis, Ming Rong Liu, Fasih A. Rahman, Michelle V. Tomczewski, Mackenzie Q. Graham, Musa Musa, Alex D. Cocco, Ken D. Stark, Joe Quadrilatero, Robin E. Duncan   +10 more
wiley   +1 more source

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, Neupert, Walter, Schwaiger, Martin   +2 more
core   +3 more sources

CoQ10 and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly

Frontiers in Aging Neuroscience, 2019
Introduction: With an aging population there is an important need for the development of effective treatments for the amelioration of cognitive decline.
Con Stough, Madeleine Nankivell, David A. Camfield, Naomi L. Perry, Andrew Pipingas, Helen Macpherson, Keith Wesnes, Keith Wesnes, Keith Wesnes, Ruchong Ou, David Hare, Judy de Haan, Geoffrey Head, Peter Lansjoen, Alena Langsjoen, Brendan Tan, Matthew P. Pase, Matthew P. Pase, Matthew P. Pase, Rebecca King, Renee Rowsell, Oliver Zwalf, Yossi Rathner, Matthew Cooke, Franklin Rosenfeldt, Franklin Rosenfeldt   +25 more
doaj   +1 more source

Chronic Progressive External Ophthalmoplegia Is Associated with a Novel Mutation in the Mitochondrial tRNA(Asn) Gene [PDF]

, 1994
Chronic progressive external ophthalmoplegia (CPEO) is caused by a decreased oxidative phosphorylation (OXPHOS) activity due to large-scale deletions of the mitochondrial genome in 50 % of the patients.
Kadenbach, B., Klopstock, Thomas, Lauber, J., Marsac, C., Reichmann, Heinz, Seibel, P.   +5 more
core   +1 more source