Results 81 to 90 of about 35,390 (246)

Different parts of the mussel Gigantidas haimaensis holobiont responded differently to deep‐sea sampling stress

open access: yesIntegrative Zoology, EarlyView.
Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN   +4 more
wiley   +1 more source

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

open access: yesAging Cell, EarlyView.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan   +15 more
wiley   +1 more source

COENZYME Q10 IN PEDIATRICS

open access: yesВопросы современной педиатрии, 2011
The article presents the description of children’s diseases related to primary and secondary disorders of cell energy exchange. Mechanisms of energotropic and antioxidant effect of ubiquinone (coenzyme Q10) in treatment of different diseases including ...
I.M. Osmanov   +2 more
doaj  

Six New Cases of 22q13.2 Gain Including TFC20: First Report of Triplication and Smallest Duplication Associated With Neurodevelopmental Delays

open access: yesClinical Genetics, EarlyView.
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot   +13 more
wiley   +1 more source

Statin therapy and neuropathy in type 1 diabetes: A cross‐sectional study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Dyslipidaemia contributes to the pathogenesis of diabetic peripheral neuropathy (DPN). While statins improve cardiovascular outcomes in diabetes, their potential neurotoxic effects remain debated. This study examined the impact of statin use on neuropathy in type 1 diabetes mellitus (T1DM). Materials and Methods Participants with T1DM (n =
Raabya Pasha   +9 more
wiley   +1 more source

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