Editorial: Ubiquitin proteasome system (UPS) and ubiquitin-independent proteasome-mediated proteolysis (UIPP) crosstalk in development and disease. [PDF]
Sharon M, Stohwasser R.
europepmc +1 more source
MicroRNAs as the critical regulators of ubiquitin-proteasome system through F-box protein targeting during tumor progression. [PDF]
Akhlaghipour I, Moghbeli M.
europepmc +1 more source
RAB40C regulates SNX9 stability <i>via</i> the ubiquitin-proteasome system and modulates the Hippo signaling pathway of prostate adenocarcinoma. [PDF]
Qin L +5 more
europepmc +1 more source
Paediatric developmental safety and the ICH E11A extrapolation of safety
British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart +6 more
wiley +1 more source
How the Ubiquitin–Proteasome System Controls Transcription
Gene transcription and ubiquitin-mediated proteolysis are two processes that have seemingly nothing in common: transcription is the first step in the life of any protein and proteolysis the last. Despite the disparate nature of these processes, a growing
William P. Tansey
exaly +2 more sources
Related searches:
The ubiquitin proteasome system and schizophrenia
The Lancet Psychiatry, 2020The ubiquitin-proteasome system is a master regulator of neural development and the maintenance of brain structure and function. It influences neurogenesis, synaptogenesis, and neurotransmission by determining the localisation, interaction, and turnover of scaffolding, presynaptic, and postsynaptic proteins.
Luza, Sandra +5 more
openaire +3 more sources
Illuminating the ubiquitin/proteasome system
Experimental Cell Research, 2010The ubiquitin/proteasome system (UPS) is responsible for the regulated processive degradation of proteins residing in the cytosol, nucleus, and endoplasmic reticulum. The two central players are ubiquitin, a small protein that is conjugated to substrates, and the proteasome, a large multi-subunit proteolytic complex that executes degradation of ...
Florian A, Salomons +2 more
openaire +2 more sources
The ubiquitin-proteasome system and endocytosis
Journal of Cell Science, 1999ABSTRACT Internalization of membrane proteins has been studied for more than three decades without solving all the underlying mechanisms. Our knowledge of clathrin-mediated endocytosis is certainly sufficient to understand the basic principles.
Strous, G J, Govers, R
openaire +3 more sources
The Ubiquitin–Proteasome System: Central Modifier of Plant Signalling
Ubiquitin is well established as a major modifier of signalling in eukaryotes. However, the extent to which plants rely on ubiquitin for regulating their lifecycle is only recently becoming apparent. This is underlined by the over-representation of genes
Ari Sadanandom +2 more
exaly +2 more sources

