Results 11 to 20 of about 299,277 (219)

How Influenza A Virus NS1 Deals with the Ubiquitin System to Evade Innate Immunity

Viruses, 2021
Ubiquitination is a post-translational modification regulating critical cellular processes such as protein degradation, trafficking and signaling pathways, including activation of the innate immune response. Therefore, viruses, and particularly influenza
Laurie-Anne Lamotte, Lionel Tafforeau
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Comparison of gene expression of metallothioneins, ubiquitin and p53 in fibroblasts from lung and skin of rats of different age

Regulatory Mechanisms in Biosystems, 2015
We studied gene expression of five metallothioneins (MT 1-5), ubiquitin and protein p53 and their products in fibroblasts culture of the skin and lungs of white rats of different ages (2 weeks, 1, 3, and 24 months) and determined its (metallothionein 1-5
Y. G. Kot, E. V. Kot, E. S. Morosova, E. E. Persky, M. A. Gritsenko, N. I. Bulankina   +5 more
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Chronic ingestion of alcohol modulates expression of ubiquitin editing enzyme A20 in lung macrophages

Multidisciplinary Respiratory Medicine, 2011
Background Alcohol abuse is involved in the pathogenesis of multiple organ disorders; the underlying mechanism is incompletely understood. The ubiquitin editing enzyme A20 is involved in regulating activities in the cell.
Huang Quan-Yong, Chen Yu-Chuan, Liu Shui-Ping   +2 more
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Interplay between the Ubiquitin Proteasome System and Ubiquitin-Mediated Autophagy in Plants

Cells, 2020
All eukaryotes rely on the ubiquitin-proteasome system (UPS) and autophagy to control the abundance of key regulatory proteins and maintain a healthy intracellular environment. In the UPS, damaged or superfluous proteins are ubiquitinated and degraded in
Tong Su, Mingyue Yang, Pingping Wang, Yanxiu Zhao, Changle Ma   +4 more
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Cryopreservation of fluorescence activated cell sorted boar spermatozoa based on extracellular ubiquitination

Czech Journal of Animal Science, 2016
The present study is focused on the methodology of fluorescence activated cell sorting (FACS) of spermatozoa stained by the antibody against extracellular surface marker ubiquitin (eUb) and subsequent protocol for their long term storage in liquid ...
A. Petelák, V. Krylov
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Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes

Frontiers in Endocrinology, 2022
The small RWD domain-containing protein called RSUME or RWDD3 was cloned from pituitary tumor cells with increasing tumorigenic and angiogenic proficiency.
Mariana Fuertes, Belén Elguero, David Gonilski-Pacin, Florencia Herbstein, Josefina Rosmino, Nicolas Ciancio del Giudice, Manuel Fiz, Lara Falcucci, Eduardo Arzt, Eduardo Arzt   +9 more
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SUMO conjugation regulates immune signalling

Fly, 2020
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore functional roles for one such PTM, the small ubiquitin-like modifier (SUMO ...
Sushmitha Hegde, Amarendranath Soory, Bhagyashree Kaduskar, Girish S. Ratnaparkhi   +3 more
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Arabidopsis‐expressing lysine‐null SUMO1 reveals a non‐essential role for secondary SUMO modifications in plants

Plant Direct, 2023
The reversible conjugation of small ubiquitin‐like modifier (SUMO) to other proteins has pervasive roles in various aspects of plant development and stress defense through its selective attachment to numerous intracellular substrates.
Thérèse C. Rytz, Juanjuan Feng, Jessica A. S. Barros, Richard D. Vierstra   +3 more
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A ubiquitin-related gene signature for predicting prognosis and constructing molecular subtypes in osteosarcoma

Frontiers in Pharmacology, 2022
Background: Ubiquitination is medicated by three classes of enzymes and has been proven to involve in multiple cancer biological processes. Moreover, dysregulation of ubiquitination has received a growing body of attention in osteosarcoma (OS ...
Nan Wei, Nan Wei, Gong Chao-yang, Gong Chao-yang, Zhou Wen-ming, Zhou Wen-ming, Lei Ze-yuan, Lei Ze-yuan, Shi Yong-qiang, Shi Yong-qiang, Zhang Shun-bai, Zhang Shun-bai, Zhang Kai, Zhang Kai, Ma Yan-chao, Ma Yan-chao, Zhang Hai-hong, Zhang Hai-hong   +17 more
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Solo or in Concert: SUMOylation in Pathogenic Fungi [PDF]

The Plant Pathology Journal
SUMOylation plays a pivotal role in DNA replication and repair, transcriptional stability, and stress response. Although SUMOylation is a conserved post-translational modification (PTM) in eukaryotes, the number, type, and function of SUMOylation ...
You-Jin Lim, Yong-Hwan Lee
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