Results 271 to 280 of about 574,104 (383)

Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity.

, 1993
Ashok N. Hegde, Alfred L. Goldberg, James H. Schwartz   +2 more
openalex   +1 more source

‘ER degradation’ of a mutant yeast plasma membrane protein by the ubiquitin‐proteasome pathway [PDF]

, 1998
Jean‐Marc Galan, B. Cantegrit, Catherine Garnier, Olivier Namy, Rosine Haguenauer‐Tsapis   +4 more
openalex   +1 more source

Cellular parameters shaping pathways of targeted protein degradation. [PDF]

Commun Biol
Cardno A, Kennedy B, Lindon C.
europepmc   +1 more source

Insights into ubiquitin chain architecture using Ub-clipping

Nature, 2019
Kirby N. Swatek, Joanne L. Usher, Anja F. Kueck, C. Gladkova, T. Mevissen, J. Pruneda, T. Skern, D. Komander   +7 more
semanticscholar   +1 more source

Antagonistic Ghd7‐OsNAC42 Complexes Modulate Carbon and Nitrogen Metabolism to Achieves Superior Quality and High Yield in Rice

Advanced Science, EarlyView.
The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou, Pingli Chen, Pingbo Li, Haozhou Gao, Jiawang Xiong, Shanshan Wan, Yuanyuan Zheng, Yufu Wang, Mufid Alam, Yingnanjun Chen, Lei Wang, Jingjing Bai, Xuan Tan, Wenting Rao, Bian Wu, Hao Zhou, Yanhua Li, Guanjun Gao, Qinglu Zhang, Jinghua Xiao, Xianghua Li, Xuelei lai, Qifa Zhang, Yuqing He   +23 more
wiley   +1 more source

There's the Rub: a novel ubiquitin-like modification linked to cell cycle regulation [PDF]

, 1998
Mark Hochstrasser
openalex   +1 more source

An insect symbiotic virus promotes the transmission of a phytoarbovirus via inhibiting E3 ubiquitin ligase Sina. [PDF]

PLoS Pathog
Wang H, Zhang J, Liu R, Li Y, Du Y, Wei T.   +5 more
europepmc   +1 more source

Ezetimibe Engineered L14‐8 Suppresses Advanced Prostate Cancer by Activating PLK1/TP53‐SAT1‐Induced Ferroptosis

Advanced Science, EarlyView.
L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang, Xiao‐wen Song, Na Zhang, Xue‐hui Li, Fan‐chen Wu, Yu‐ang Wei, Dong‐liang Xu, Ling‐fan Xu, Fu‐wen Yuan   +8 more
wiley   +1 more source

Functional and physical characterization of the cell cycle ubiquitin-conjugating enzyme CDC34 (UBC3). Identification of a functional determinant within the tail that facilitates CDC34 self-association

, 1994
Christopher P. Ptak, John A. Prendergast, Robert Hodgins, C.M. Kay, Vincent Chau, Michael J. Ellison   +5 more
openalex   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source