Results 271 to 280 of about 574,104 (383)
‘ER degradation’ of a mutant yeast plasma membrane protein by the ubiquitin‐proteasome pathway [PDF]
Jean‐Marc Galan+4 more
openalex +1 more source
Cellular parameters shaping pathways of targeted protein degradation. [PDF]
Cardno A, Kennedy B, Lindon C.
europepmc +1 more source
Insights into ubiquitin chain architecture using Ub-clipping
Kirby N. Swatek+7 more
semanticscholar +1 more source
The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou+23 more
wiley +1 more source
There's the Rub: a novel ubiquitin-like modification linked to cell cycle regulation [PDF]
Mark Hochstrasser
openalex +1 more source
An insect symbiotic virus promotes the transmission of a phytoarbovirus via inhibiting E3 ubiquitin ligase Sina. [PDF]
Wang H+5 more
europepmc +1 more source
L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang+8 more
wiley +1 more source
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie+9 more
wiley +1 more source