Results 211 to 220 of about 187,561 (340)

Analysis of Ubiquitination In Vivo Using a Transgenic Mouse Model [PDF]

, 2001
Maria Tsirigotis, Sherry Thurig, Manon Dubé, Barbara C. Vanderhyden, M. Zhang, Douglas A. Gray   +5 more
openalex   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
wiley   +1 more source

Post-translational modifications of cancer immune checkpoints: mechanisms and therapeutic strategies. [PDF]

Mol Cancer
Jia H, Jiang L, Shen X, Ye H, Li X, Zhang L, Hu Y, Song D, Jia H, Wang Z.   +9 more
europepmc   +1 more source

Tunicamycin induces ubiquitination and degradation of apolipoprotein B in HepG2 cells [PDF]

, 2001
Wei Liao, Lawrence Chan
openalex   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Molecular features defining the efficiency of bioPROTACs. [PDF]

Commun Biol
Winkelvoß D, Vukovic D, Hänny AC, Riermeier L, Udovcic A, Kolibius J, Honegger A, Mittl PRE, Michel E, Hansen S, Plückthun A.   +10 more
europepmc   +1 more source

The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C [PDF]

, 2001
Heiwa Okuda, Kojiro Saitoh, Syu-ichi Hirai, Kazuhiro Iwaï, Yasuyuki Takaki, Masaya Baba, Nagahiro Minato, Shigeo Ohno, Taro Shuin   +8 more
openalex   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

Post-Translational Modification of p62: Roles and Regulations in Autophagy. [PDF]

Cells
Xiao S, Yu Y, Liao M, Song D, Xu X, Tian L, Zhang R, Lyu H, Guo D, Zhang Q, Chen XZ, Zhou C, Tang J.   +12 more
europepmc   +1 more source

Regulation of Ubiquitination and Degradation of p53 in Unstressed Cells through C-terminal Phosphorylation [PDF]

, 2001
Mikhail V. Chernov, Lora Jh Bean, Natalia Lerner, George R. Stark   +3 more
openalex   +1 more source