Results 151 to 160 of about 97,644 (305)

From wild to tamed: Reimagining novel crops through omics and local plant diversity

PLANTS, PEOPLE, PLANET, EarlyView.
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá, Pablo D. Cárdenas   +1 more
wiley   +1 more source

Sea urchin embryo cell aggregation with UDP and UDP-sugars [PDF]

, 1992
Cell surface characteristics and properties are important due to their involvement in embryogenesis, oncogenesis and metastasis. Sugar chains reaching away from the cell surface are the first line of contact between two approaching cells ...
Golbert, Miriam S.
core   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo, Simona Daniele, Davide Bianchi, Lara Russo, Stefano Capaldi, Maria Letizia Trincavelli, Ivano Eberini   +6 more
wiley   +1 more source

Advanced Hybrid Techniques for Cyberattack Detection and Defense in IoT Networks

SECURITY AND PRIVACY, Volume 8, Issue 2, March/April 2025.
ABSTRACT The Internet of Things (IoT) represents a vast network of devices connected to the Internet, making it easier for users to connect to modern technology. However, the complexity of these networks and the large volume of data pose significant challenges in protecting them from persistent cyberattacks, such as distributed denial‐of‐service (DDoS)
Zaed S. Mahdi, Rana M. Zaki, Laith Alzubaidi   +2 more
wiley   +1 more source

UDP-galactose 4-epimerase (GALE) [PDF]

, 2013
UDP-galactose 4-epimerase (GALE; EC 5.1.3.2; UniProt: Q14376) catalyses the interconversion of UDP-galactose and UDP-glucose (figure 1a). In the majority of eukaryotes studied to date, the enzyme is also able to interconvert UDP-N-acetylgalactosamine ...
McCorvie, Thomas, Timson, David
core  

Whole‐transcriptome sequencing analyses identified exosomal circular RNAs in the plasma of pancreatic cancer patients as novel blood‐based biomarkers of disease

VIEW, EarlyView.
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He, Yang Di, Lixiang Sun, Zhirong Wu, Mengting Luo, Xin Zhang, Huaqin Sun, Wanli Xu, Wenchuan Wu, Boheng Zhang, Jin Wang   +10 more
wiley   +1 more source

[UDP-glucuronosyltransferase].

Nihon eiseigaku zasshi. Japanese journal of hygiene, 2002
UDP-glucuronosyltransferases (UGTs) represent a family of enzymes that glucuronidate many internal substances and drugs. This family acts as a drug metabolism phase II reactor in the liver and comprises one of the major protective mechanisms from toxic chemical substances. UGTs have two subfamilies; UGT1 and UGT2.
Yoshihiro, Maruo, Hiroshi, Sato
openaire   +1 more source

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

VIEW, EarlyView.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian, Zhiqian Huang, Keke Zhang, Jing Lin, Jia You, Yi Lu, Xiangjia Zhu   +6 more
wiley   +1 more source

The prototype DynamiX camera system – a high‐frame‐rate high‐dynamic‐range hard X‐ray integrating detector for fourth‐generation synchrotrons

Journal of Synchrotron Radiation, EarlyView.
This paper presents the first results from the DynamiX X‐ray imaging detector developed by the UK's Science and Technology Facilities Council for a new generation of photon light sources. Operating at a continuous frame rate of 534 kHz and with a per‐pixel per‐frame dynamic range of roughly five orders of magnitude, this work is the first step in ...
Simon Knowles, Darren Ballard, Dominic Banks, Stephen Bell, Manuele Bettelli, Ivan Church, Alex Dainty, Adam Davis, Vishal Dhamgaye, Oliver Fox, Marcus French, Thomas Gardiner, Navid Ghorbanian, Josh Harris, Matt Hart, Aswathi Koorikkat, Matt Larkin, John Lipp, John Matheson, Tim Nicholls, Joseph Nobes, Mark Prydderch, Kawal Sawhney, Matthew C. Veale, Matthew D. Wilson, Silvia Zanettini   +25 more
wiley   +1 more source

UDP-glycosyltransferases act as key determinants of host plant range in generalist and specialist Spodoptera species. [PDF]

Phytophagous insects have evolved sophisticated detoxification systems to overcome the antiherbivore chemical defenses produced by many plants. However, how these biotransformation systems differ in generalist and specialist insect species and their role
X Geng (13283823), S Zhou (7455506), C Bass (16100450), H Wang (7713587), A Hayward (7736006), B Li (6415280), Y Xiao (9729080), BJ Hunt (21949778), J Song (9887243), K Zuo (11727179), H Zhou (7704704)   +10 more
core