Results 1 to 10 of about 13,761 (153)

UDP-glucosyltransferase OsUGT75A promotes submergence tolerance during rice seed germination [PDF]

Nature Communications, 2023
Submergence stress represents a major obstacle limiting the application of direct seeding in rice cultivation. Under flooding conditions, coleoptile elongation can function as an escape strategy that contributes to submergence tolerance during seed ...
Yongqi He, Shan Sun, Jia Zhao, Zhibo Huang, Liling Peng, Chengwei Huang, Zhengbin Tang, Qianqian Huang, Zhoufei Wang   +8 more
doaj   +4 more sources

A Ubiquitously Expressed UDP-Glucosyltransferase, UGT74J1, Controls Basal Salicylic Acid Levels in Rice [PDF]

Plants, 2021
Salicylic acid (SA) is a phytohormone that regulates a variety of physiological and developmental processes, including disease resistance. SA is a key signaling component in the immune response of many plant species.
Daisuke Tezuka, Hideyuki Matsuura, Wataru Saburi, Haruhide Mori, Ryozo Imai   +4 more
doaj   +6 more sources

UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice [PDF]

Nature Communications, 2020
Increasing grain yield needs to be put in the context of environmental stress. Here, the authors reveal that a UDP-glucosyltransferase is associated with regulation of rice grain size, abiotic stress tolerance, flavonoid-mediated auxin signaling, and ...
Nai-Qian Dong, Yuwei Sun, Tao Guo, Chuan-Lin Shi, Yi-Min Zhang, Yi Kan, You-Huang Xiang, Hai Zhang, Yi-Bing Yang, Ya-Chao Li, Huai-Yu Zhao, Hong-Xiao Yu, Zi-Qi Lu, Yong Wang, Wang-Wei Ye, Jun-Xiang Shan, Hong-Xuan Lin   +16 more
doaj   +2 more sources

Identification and Functional Characterisation of Two Oat UDP-Glucosyltransferases Involved in Deoxynivalenol Detoxification [PDF]

Toxins, 2022
Oat is susceptible to several Fusarium species that cause contamination with different trichothecene mycotoxins. The molecular mechanisms behind Fusarium resistance in oat have yet to be elucidated.
Alfia Khairullina, Nikos Tsardakas Renhuldt, Gerlinde Wiesenberger, Johan Bentzer, David B. Collinge, Gerhard Adam, Leif Bülow   +6 more
doaj   +4 more sources

Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]

Nature Communications
Collagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim, Zhenhang Chen, Sara Andrea Espinosa Garcia, Christoph Buhlheller, Botao Zhang, Stephen J. Richards, Tingfei Chen, Jingjing Wu, Ronald C. Bruntz, Marisa E. Gilliam, Mitsuo Yamauchi, Bo Liang, Houfu Guo   +12 more
doaj   +2 more sources

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub-Types. [PDF]

Biotechnol Bioeng
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Catella CM, Sarma S, Hinesley CM, Febo CE, Breau KA, Durmusoglu D, Purnell E, Magness ST, Hall CK, Menegatti S, Crook N.   +10 more
europepmc   +2 more sources

Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside [PDF]

Toxins, 2015
Glycosylation is an important plant defense mechanism and conjugates of Fusarium mycotoxins often co-occur with their parent compounds in cereal-based food and feed.
Herbert Michlmayr, Alexandra Malachová, Elisabeth Varga, Jana Kleinová, Marc Lemmens, Sean Newmister, Ivan Rayment, Franz Berthiller, Gerhard Adam   +8 more
doaj   +2 more sources

The whole-genome map of Astragalus mongholicus provides ideas for the synthesis of glutathione and flavonoid [PDF]

BMC Genomics
Background The legume Astragalus mongholicus (A. mongholicus) has a wide variety of medicinal properties. Based on the genome of A. mongholicus, this study intended to investigate the phylogenetic position of A.
Miaozhuo Yao, Fanshu Gong, Yunhui Liang, Huixia Gao, Pengfei Zhang, Yaling Liu   +5 more
doaj   +2 more sources

Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues

Nature Communications, 2021
The Clostridium difficile virulence factors TcdA and TcdB contain a glucosyltransferase domain (GTD), which has both glucohydrolase (GH) and glucosyltransferase (GT) activities. Here, the authors characterize the transition state features of the TcdA and
Ashleigh S. Paparella, Briana L. Aboulache, Rajesh K. Harijan, Kathryn S. Potts, Peter C. Tyler, Vern L. Schramm   +5 more
doaj   +1 more source

Role of UDP-glucose ceramide glucosyltransferase in venous malformation

Frontiers in Cell and Developmental Biology, 2023
Venous malformation (VM) results from the abnormal growth of the vasculature; however, the detailed molecular mechanism remains unclear. As a glycosyltransferase, UDP-glucose ceramide glucosyltransferase (UGCG) is localized to the Golgi body and is a key
Sheng Chen, Yuan Wang, Liangliang Kong, Yi Ji, Jie Cui, Weimin Shen   +5 more
doaj   +1 more source