Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein. [PDF]
Drug Metab Dispos, 2018 Kim K, Zheng F, Zhan CG.
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In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters. [PDF]
Molecules, 2019 Kim S +8 more
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Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation. [PDF]
Pharmaceutics, 2018 Shrestha R +7 more
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International Evaluation of Research and Doctoral Training at the University of Helsinki 2005-2010 : RC-Specific Evaluation of MEDCHEMBIO - Medicinal Chemistry and Biochemistry Research Group [PDF]
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Glucuronidation represents a major pathway which enhances the elimination of many lipophilic xenobiotics and endobiotics to more water-soluble compounds. The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen ...
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The Journal of Steroid Biochemistry and Molecular Biology, 1992The glucuronidation of steroids is a major process necessary for their elimination in the bile and urine. In general, steroid glucuronides are biologically less reactive than their parent steroids. However, in some cases often associated with disease and steroid therapy, more reactive or toxic glucuronides may be formed.
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Human UDP-Glucuronosyltransferase 2B7
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