Results 171 to 180 of about 53,054 (215)

The Ontogeny of UDP-glucuronosyltransferase Enzymes, Recommendations for Future Profiling Studies and Application Through Physiologically Based Pharmacokinetic Modelling

Clinical Pharmacokinetics, 2018
J. Badée, S. Fowler, S. Wildt, A. Collier, S. Schmidt, N. Parrott   +5 more
semanticscholar   +1 more source

Characterization of UDP-glucuronosyltransferase genes and their possible roles in multi-insecticide resistance in Plutella xylostella (L.).

Pest Management Science, 2018
Xiuxia Li, Haiyan Shi, Xiwu Gao, P. Liang   +3 more
semanticscholar   +1 more source

A Molecular‐Splicing Strategy for Constructing a Near‐Infrared Fluorescent Probe for UDP‐Glucuronosyltransferase 1A1

Angewandte Chemie - International Edition, 2021
Jian Gao, Tony D James
exaly  

Characterisation and Regulation of UDP-Glucuronosyltransferases

1991
Many drugs, xenobiotics and endogenous compounds are metabolised via common two stage pathway, which was designated as phase 1 (oxidative metabolism) and phase II (conjugation) by Williams (1). Glucuronidation reactions catalysed by the UDP-glucuronosyltransferases (UDPGTs) is arguably the major conjugation system of phase II metabolism. The metabolism
openaire   +1 more source

Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects.

Molecular Pharmaceutics, 2016
Eisuke Miyauchi, M. Tachikawa, X. Declèves, Yasuo Uchida, J. Bouillot, C. Poitou, J. Oppert, S. Mouly, J. Bergmann, T. Terasaki, J. Scherrmann, C. Lloret-Linares   +11 more
semanticscholar   +1 more source

DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS

Drug Metabolism And Disposition, 2004
J. A. Williams, R. Hyland, Barry C. Jones, Dennis A. Smith, Susan I. Hurst, T. Goosen, Vincent C. Peterkin, Jeffrey R. Koup, S. Ball   +8 more
semanticscholar   +1 more source

Glucuronidation and the UDP - glucuronosyltransferases

The Biomedical & Life Sciences Collection, 2007
Peter Mackenzie, John Miners
openaire   +1 more source

Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi).

Toxicology and Applied Pharmacology, 2015
Xin-xin Wang, X. Lv, Shi-yang Li, Jie Hou, Jing Ning, Jia-Yue Wang, Yun-feng Cao, Guangbo Ge, Bin Guo, Ling Yang   +9 more
semanticscholar   +1 more source

UDP-glucuronosyltransferase activities

Biochemical Pharmacology, 1983
Karl Walter Bock, Brian Burchell, Geoffrey J. Dutton, Osmo Hänninen, Gerard J. Mulder, Ida S. Owens, Gérard Siest, Thomas R. Tephly   +7 more
openaire   +1 more source

Multiple roles for UDP-glucuronosyltransferase (UGT)2B15 and UGT2B17 enzymes in androgen metabolism and prostate cancer evolution.

Journal of Steroid Biochemistry and Molecular Biology, 2015
Louis Gauthier-Landry, A. Bélanger, O. Barbier   +2 more
semanticscholar   +1 more source